Jung Won-Mo, Lee In-Seon, Wallraven Christian, Ryu Yeon-Hee, Park Hi-Joon, Chae Younbyoung
Acupuncture &Meridian Science Research Center, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.
1] Acupuncture &Meridian Science Research Center, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea [2] Department of Internal Medicine: Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Tübingen, Germany [3] IMPRS for Cognitive and Systems Neuroscience, University Tübingen, Tübingen, Germany.
Sci Rep. 2015 Jul 27;5:12455. doi: 10.1038/srep12455.
We investigated commonalities and differences in brain responses to enhanced bodily attention around acupuncture points with and without stimulation. Fourteen participants received acupuncture needles at both PC6 and HT7 acupoints in the left hand. To enhance bodily attention to acupoints, participants responded to the locations of stimulations in a two-alternative forced choice task. Two fMRI scans were taken in a block design: session 1 labeled with manual stimulation (genuine stimulation) and session 2 labeled with electro-acupuncture (pseudo-stimulation). To compare cortical activation patterns, data were analyzed using the Freesurfer software package. Both genuine-and pseudo-stimulation resulted in brain activations in the insula, anterior cingulate cortex, secondary somatosensory cortex, superior parietal cortex, and brain deactivation in the medial prefrontal cortex, posterior cingulate cortex, inferior parietal cortex, and the parahippocampus. Genuine acupuncture stimulation exhibited greater brain activation in the posterior insula, posterior operculum and the caudal part of the anterior cingulate cortex, compared with pseudo-stimulation. We demonstrated that enhanced bodily attention triggered by genuine acupuncture stimulation can activate the salience network and deactivate the default mode network regardless of the type of stimulation. The component of enhanced attention to a certain part of the body is significant in the brain response to acupuncture stimulation.
我们研究了在针刺穴位有刺激和无刺激情况下，大脑对增强身体注意力的反应的异同。14名参与者左手的内关穴（PC6）和神门穴（HT7）均接受了针灸针。为增强对穴位的身体注意力，参与者在二选一强制选择任务中对刺激位置做出反应。采用组块设计进行了两次功能磁共振成像扫描：第1次扫描标记为手法刺激（真刺激），第2次扫描标记为电针刺激（假刺激）。为比较皮质激活模式，使用Freesurfer软件包对数据进行分析。真刺激和假刺激均导致脑岛、前扣带回皮质、次级体感皮质、顶上叶皮质激活，以及内侧前额叶皮质、后扣带回皮质、顶下叶皮质和海马旁回的脑失活。与假刺激相比，真针刺刺激在脑岛后部、岛盖后部和前扣带回皮质尾部表现出更大的脑激活。我们证明，无论刺激类型如何，真针刺刺激引发的增强身体注意力均可激活突显网络并使默认模式网络失活。对身体某一部位增强注意力的成分在大脑对针刺刺激的反应中具有重要意义。
