Lomoro P, Simonetti I, Vinci G, Fichera V, Tarotto L, Trovato P, Prevedoni Gorone M S
Department of Diagnostic Medicine Institute of Radiology, IRCCS San Matteo University Hospital Foundation, Pavia, Italy.
Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
Eur J Radiol Open. 2019 Feb 14;6:97-100. doi: 10.1016/j.ejro.2019.02.002. eCollection 2019.
Langerhans cell histiocytosis (LCH) is a rare disease of the myeloid precursor cells, it predominantly occurs in the skull and long bones as unifocal bone lesions. Aneurysmal bone cysts (ABC) are benign, expansive and lytic bone. Reports of secondary ABC occurring in LCH are rare, having only been reported twice in the skull. Here, we report the first case of LCH masquerading as ABC in a 14-month-old female child who presented with a rapidly growing mass in her left femur. The lesion had typical radiological features of ABC, and only histological examination revealed the presence of cells suggestive of LCH.
朗格汉斯细胞组织细胞增多症（LCH）是一种罕见的髓系前体细胞疾病，主要表现为颅骨和长骨的单发性骨病变。骨囊肿（ABC）是良性、膨胀性、溶骨性病变。LCH继发ABC的报道罕见，仅在颅骨中有两例报道。在此，我们报告首例14个月大女童LCH伪装成ABC的病例，该女童左股骨出现快速生长的肿块。该病变具有ABC典型的放射学特征，仅组织学检查发现存在提示LCH的细胞。
