转移性和非转移性恶性肿瘤中钙和钠的肾脏处理
Renal handling of calcium and sodium in metastatic and non-metastatic malignancy.
作者信息
Heller S R, Hosking D J
出版信息
Br Med J (Clin Res Ed). 1986 Mar 1;292(6520):583-6. doi: 10.1136/bmj.292.6520.583.
Abstract
Investigation of the renal handling of calcium and sodium in rehydrated patients with hypercalcaemia associated with malignancy showed enhanced reabsorption of calcium in most cases. This was a feature of both metastatic and non-metastatic malignancy, and in this respect the patients were indistinguishable from patients with primary hyperparathyroidism. As the increased calcium reabsorption was inversely correlated with the rate of excretion of sodium modest salt loading can be used to inhibit this process. This is an important practical aspect of the treatment of patients with this type of hypercalcaemia.
摘要
对伴有恶性肿瘤的高钙血症患者补液后肾脏对钙和钠处理情况的研究表明，在大多数情况下钙的重吸收增强。这是转移性和非转移性恶性肿瘤的共同特征，在这方面，这些患者与原发性甲状旁腺功能亢进患者并无差异。由于钙重吸收增加与钠排泄率呈负相关，适度增加盐摄入可用于抑制这一过程。这是这类高钙血症患者治疗中的一个重要实际方面。
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本文引用的文献
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