Shirakusa T, Shigematsu N, Yoshida T, Saito R, Katayama N, Inokuchi K
J Thorac Cardiovasc Surg. 1978 Aug;76(2):262-5.
Absolute numbers of T cells were measured in a series of 84 patients with bronchogenic carcinoma and were compared with T cell percent with regard to clinical stage, course, and histologic type. Although T cell percent declined in accordance with the advancement of stage, the differences between the stages were not statistically significant. On the other hand, the absolute number of T cells decreased prominently in Stages III and IV as compared to Stages I and II (p less than 0.05 between Stages I and III, P less than 0.001 between Stages I and IV, and p less than 0.05 between Stages II and IV). Likewise in patients who were followed serially after resection, the absolute number of T cels correlated well with the postoperative course. These results lead us to the conclusion that it is more useful estimate the absolute T cell count rather than T cell percentage in lung cancer.
对84例支气管癌患者的T细胞绝对数量进行了检测，并就临床分期、病程和组织学类型对T细胞百分比进行了比较。尽管T细胞百分比随着分期的进展而下降，但各分期之间的差异无统计学意义。另一方面，与I期和II期相比，III期和IV期的T细胞绝对数量显著减少（I期和III期之间p<0.05，I期和IV期之间P<0.001，II期和IV期之间p<0.05）。同样，在切除术后进行连续随访的患者中，T细胞绝对数量与术后病程密切相关。这些结果使我们得出结论，在肺癌中，估计T细胞绝对计数比T细胞百分比更有用。
