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肾孤立性纤维瘤的临床病理特征:单机构经验

Clinicopathological characteristics of renal solitary fibrous tumor: A single institution experience.

作者信息

Fu Weijin, Bing Qin, JingJing Zeng, Lijian Lu, Zhibin Xie, Qijian Ding, Jiwen Cheng

机构信息

Department of Urology, The First Affiliated Hospital of GuangXi Medical University,NanNing.

Department of Urology, The Eighth Affiliated Hospital of GuangXi Medical University, GuiGang.

出版信息

Medicine (Baltimore). 2019 Feb;98(8):e14618. doi: 10.1097/MD.0000000000014618.

Abstract

To analyze the clinical characteristics, treatment modalities and outcomes of adult renal solitary fibrous tumors (SFT) treated at a single institution. Demographic, diagnostic, surgical, and pathological findings of patients who had undergone radical nephrectomy (RN) due to renal SFT were collected from the database of a single institution and were retrospectively reviewed. Ten patients (6 men and 4 women) were diagnosed with renal SFT in our institution between January 1, 2000 and December 31, 2016. The mean age was 50.9 ± 8.2 years (range, 38-63 years). Of the 10 patients, 6 were asymptomatic, 2 presented with flank pain, 1 presented with abdominal discomfort, and 1 presented with haematuria. Computed tomography scans were obtained for all patients. Open RN was performed on 6 patients, and laparoscopic RN was performed on 4 patients. The mean tumor size was 10.23 ± 4 cm (range, 5.3-19 cm). Pathological diagnosis revealed that the tumors in 8 patients were benign, while those in the other 2 patients were malignant renal SFT. No recurrence occurred during a mean follow-up period of 47.3 ± 21.5 months (range, 16-85 months). Renal SFT is extremely rare, and its diagnosis may be challenging because of a lack of typical imaging manifestations. RN is a safe treatment modality for benign or low-grade malignant renal SFT, ensuring favorable outcomes.

摘要

分析在单一机构接受治疗的成人肾孤立性纤维瘤(SFT)的临床特征、治疗方式及预后。从单一机构的数据库中收集因肾SFT接受根治性肾切除术(RN)患者的人口统计学、诊断、手术及病理结果,并进行回顾性分析。2000年1月1日至2016年12月31日期间,我院共诊断出10例肾SFT患者(6例男性,4例女性)。平均年龄为50.9±8.2岁(范围38 - 63岁)。10例患者中,6例无症状,2例出现侧腹痛,1例出现腹部不适,1例出现血尿。所有患者均行计算机断层扫描。6例行开放性RN,4例行腹腔镜RN。平均肿瘤大小为10.23±4 cm(范围5.3 - 19 cm)。病理诊断显示,8例患者的肿瘤为良性,另外2例为恶性肾SFT。平均随访47.3±

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