Thiede A, Deltz E
Langenbecks Arch Chir. 1978 Aug 18;346(2):119-27. doi: 10.1007/BF01261398.
From the inbred rat stains F344, LEW and Brown-Norway (BN), the following combinations were formed: syngeneic (LEW--LEW), weakly allogeneic (F344--LEW) and strongly allogeneic (BN--LEW). A small intestine segment was transplanted using the by-pass technique; after 10 days the graft was removed and histologically investigated. The strongest rejection was found in the lymphatic tissue and the epithelium of the small intestinal transplant. The immunogenetical difference is significant for the survival of the graft: the greater the immunogenetical difference between donor and host, the more severe the morphologically demonstrable rejection reaction.
从近交系大鼠品系F344、LEW和棕色挪威大鼠（BN）中，形成了以下组合：同基因（LEW-LEW）、弱异基因（F344-LEW）和强异基因（BN-LEW）。采用旁路技术移植一段小肠；10天后取出移植物并进行组织学研究。在小肠移植物的淋巴组织和上皮中发现了最强的排斥反应。免疫遗传学差异对移植物的存活具有重要意义：供体和宿主之间的免疫遗传学差异越大，形态学上可证实的排斥反应就越严重。
