Scherer H, Schmidtmayer E, Hirche H
Laryngol Rhinol Otol (Stuttg). 1978 Aug;57(8):773-8.
The method of a calorically induced long time stimulation is shown. Appr. 15 minutes after begin fo stimulation a nystagmus plateau can be observed. We used this plateau to demonstrate the effects of three cerebral vasoactive drugs--Bencyclane, Flunarizine and Naftidrofuryl-Hydrogenoxalate in a randomized double blind study. All of them depressed the nystagmus significantly. Naftidrofuryl by 38.4 +/- 4.6%, Flunarizine by 31 +/- 4.5% and Bencyclane by 25.1 +/- 3.8%. The depressing mechanism of Flunarizine is partly due to sedation.