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腹膜假黏液瘤的细胞减灭术及术中热灌注胸腹联合化疗(HITAC)的围手术期管理

Perioperative management of cytoreductive surgery and hyperthermic intraoperative thoraco-abdominal chemotherapy (HITAC) for pseudomyxoma peritonei.

作者信息

Solanki Sohan Lal, Bajaj Jhanvi S, Rahman Febin, Saklani Avanish P

机构信息

Department of Anaesthesiology, Critical Care and Pain, Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, Maharashtra, India.

Gastro-Intestinal Services, Department of Surgical Oncology, Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, Maharashtra, India.

出版信息

Indian J Anaesth. 2019 Feb;63(2):134-137. doi: 10.4103/ija.IJA_825_18.

Abstract

Peritoneal carcinomatosis is intraperitoneal spread of gastrointestinal and gynaecological cancers. Cytoreductive surgeries and hyperthermic intraperitoneal chemotherapy offers survival benefits in these cases. Spread of peritoneal carcinomatosis to thorax pose challenges to surgeon and anaesthesiologist. Haemodynamic, temperature and coagulopathy monitoring as well as intraoperative airway pressure, pre- and postoperative pulmonary function test monitoring is required in these cases where diaphragm excision is done and intraoperative intra peritoneal as well as pleural chemotherapy is given. We are reporting a case of pseudomyxoma peritonei involving the abdomen and left side of pleura and lung, posted for cytoreductive surgery and hyperthemic chemotherapy to abdomen and thorax, i.e., hyperthemic intraoperative thoraco-abdominal chemotherapy.

摘要

腹膜癌病是胃肠道和妇科癌症的腹膜内播散。细胞减灭术和腹腔内热灌注化疗在这些病例中可带来生存益处。腹膜癌病扩散至胸部给外科医生和麻醉医生带来了挑战。在进行膈肌切除以及术中给予腹腔内和胸膜内化疗的这些病例中,需要进行血流动力学、体温和凝血功能监测,以及术中气道压力、术前和术后肺功能测试监测。我们报告一例腹膜假黏液瘤累及腹部及左侧胸膜和肺的病例,该患者接受细胞减灭术以及腹部和胸部的热灌注化疗,即术中胸腹热灌注化疗。

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