围手术期腹腔内高压雾化化疗的关注点与管理：两例报告
Perioperative concerns and management of pressurised intraperitoneal aerosolised chemotherapy: Report of two cases.
作者信息
Solanki Sohan Lal, Kumar Pooja P, DeSouza Ashwin, Saklani Avanish P
机构信息
Department of Anesthesiology, Critical Care and Pain, Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, Maharashtra, India.
Department of Surgical Oncology, Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, Maharashtra, India.
出版信息
Indian J Anaesth. 2018 Mar;62(3):225-228. doi: 10.4103/ija.IJA_623_17.
Abstract
Pressurised intraperitoneal aerosolised chemotherapy (PIPAC) is a new, mostly supportive approach to help patients with advanced peritoneal metastasis to increase the lifespan. It carries occupational hazards to health-care workers and especially anaesthesiologist during the procedure. The aerosolised chemotherapy can also cause chemical peritonitis and organ dysfunction in the perioperative period. In this case report, we present the report of two cases and discuss the perioperative concerns and management related to PIPAC.
摘要
腹腔内加压雾化化疗（PIPAC）是一种新型的、主要起支持作用的方法，旨在帮助晚期腹膜转移患者延长生存期。在该治疗过程中，它会给医护人员尤其是麻醉医生带来职业健康风险。雾化化疗在围手术期还可能导致化学性腹膜炎和器官功能障碍。在本病例报告中，我们呈现了两例病例的报告，并讨论了与PIPAC相关的围手术期问题及处理措施。
相似文献
1
Perioperative concerns and management of pressurised intraperitoneal aerosolised chemotherapy: Report of two cases.围手术期腹腔内高压雾化化疗的关注点与管理：两例报告
Indian J Anaesth. 2018 Mar;62(3):225-228. doi: 10.4103/ija.IJA_623_17.
2
The Feasibility of Pressurised Intraperitoneal Aerosolised Virotherapy (PIPAV) to Administer Oncolytic Adenoviruses.腹腔内加压雾化病毒疗法（PIPAV）给药溶瘤腺病毒的可行性
Pharmaceutics. 2021 Nov 30;13(12):2043. doi: 10.3390/pharmaceutics13122043.
3
Anaesthesia considerations and techniques for Pressurised IntraPeritoneal Aerosol Chemotherapy (PIPAC).腹腔内高压雾化化疗（PIPAC）的麻醉注意事项及技术
Pleura Peritoneum. 2020 Nov 17;5(4):20190013. doi: 10.1515/pp-2019-0013. eCollection 2020 Nov.
4
[Pressurised intraperitoneal aerosol chemotherapy (PIPAC) for the treatment of peritoneal metastases].[腹腔内加压气雾化疗（PIPAC）治疗腹膜转移瘤]
Ugeskr Laeger. 2019 Oct 14;181(20A).
5
Quality of life of patients with end-stage peritoneal metastasis treated with Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC).接受腹腔加压气溶胶化疗（PIPAC）治疗的终末期腹膜转移患者的生活质量
Eur J Surg Oncol. 2015 Oct;41(10):1379-85. doi: 10.1016/j.ejso.2015.06.001. Epub 2015 Jun 21.
6
[Perioperative safety of intraperitoneal aerosol chemotherapy : Analysis of our first 111 pressurized intraperitoneal aerosol chemotherapy (PIPAC) procedures].[腹腔内雾化化疗的围手术期安全性：对我们最初111例加压腹腔内雾化化疗（PIPAC）手术的分析]
Chirurg. 2019 Feb;90(2):137-145. doi: 10.1007/s00104-018-0667-5.
7
Detection of free intraperitoneal tumour cells in peritoneal lavage fluid from patients with peritoneal metastasis before and after treatment with pressurised intraperitoneal aerosol chemotherapy (PIPAC).检测接受腹腔内高压气溶胶化疗（PIPAC）治疗前后腹膜转移患者腹腔灌洗液中的游离腹腔内肿瘤细胞。
J Clin Pathol. 2019 May;72(5):368-372. doi: 10.1136/jclinpath-2018-205683. Epub 2019 Feb 12.
8
Repetitive electrostatic pressurised intraperitoneal aerosol chemotherapy (ePIPAC) with oxaliplatin as a palliative monotherapy for isolated unresectable colorectal peritoneal metastases: protocol of a Dutch, multicentre, open-label, single-arm, phase II study (CRC-PIPAC).重复静电加压腹腔内气溶胶化疗（ePIPAC）联合奥沙利铂作为不可切除结直肠腹膜转移孤立灶的姑息性单药治疗：一项荷兰多中心、开放标签、单臂、Ⅱ期研究（CRC-PIPAC）的方案。
BMJ Open. 2019 Jul 27;9(7):e030408. doi: 10.1136/bmjopen-2019-030408.
9
Pressurised intraperitoneal aerosol chemotherapy: rationale, evidence, and potential indications.加压腹腔内气溶胶化疗：原理、证据和潜在适应证。
Lancet Oncol. 2019 Jul;20(7):e368-e377. doi: 10.1016/S1470-2045(19)30318-3.
10
Safety and feasibility of pressurized intraperitoneal aerosol chemotherapy (PIPAC) associated with systemic chemotherapy: an innovative approach to treat peritoneal carcinomatosis.腹腔内加压气雾化疗（PIPAC）联合全身化疗的安全性和可行性：一种治疗腹膜癌病的创新方法。
World J Surg Oncol. 2016 Apr 29;14:128. doi: 10.1186/s12957-016-0892-7.
引用本文的文献
1
Pressurized intraperitoneal aerosol chemotherapy (PIPAC): updated systematic review using the IDEAL framework.腹腔内加压气雾化疗（PIPAC）：使用IDEAL框架的最新系统评价
Br J Surg. 2022 Dec 13;110(1):10-18. doi: 10.1093/bjs/znac284.
2
Pressurized intraperitoneal aerosol chemotherapy: a review of the introduction of a new surgical technology using the IDEAL framework.加压腹腔内气溶胶化疗：使用 IDEAL 框架引入新手术技术的回顾。
BJS Open. 2020 Apr;4(2):206-215. doi: 10.1002/bjs5.50257. Epub 2020 Jan 19.
3
Society of Onco-Anaesthesia and Perioperative Care consensus guidelines for perioperative management of patients for cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC).肿瘤麻醉与围手术期护理学会关于减瘤手术和热灌注化疗（CRS-HIPEC）患者围手术期管理的共识指南。
Indian J Anaesth. 2019 Dec;63(12):972-987. doi: 10.4103/ija.IJA_765_19. Epub 2019 Dec 11.
4
Perioperative management of cytoreductive surgery and hyperthermic intraoperative thoraco-abdominal chemotherapy (HITAC) for pseudomyxoma peritonei.腹膜假黏液瘤的细胞减灭术及术中热灌注胸腹联合化疗（HITAC）的围手术期管理
Indian J Anaesth. 2019 Feb;63(2):134-137. doi: 10.4103/ija.IJA_825_18.
5
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: Fluid and temperature remain the culprit!减瘤手术与腹腔热灌注化疗：液体和温度仍是关键因素！
Indian J Anaesth. 2018 Mar;62(3):162-165. doi: 10.4103/ija.IJA_170_18.
本文引用的文献
1
Pressurized intraperitoneal aerosol chemotherapy (PIPAC) as a neoadjuvant therapy before cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.在肿瘤细胞减灭术和热灌注化疗前，采用腹腔内加压气雾化疗（PIPAC）作为新辅助治疗。
World J Surg Oncol. 2016 Sep 27;14(1):253. doi: 10.1186/s12957-016-1008-0.
2
Minimizing Occupational Exposure to Antineoplastic Agents.
J Infus Nurs. 2016 Sep-Oct;39(5):307-13. doi: 10.1097/NAN.0000000000000183.
3
Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) with Low-Dose Cisplatin and Doxorubicin in Gastric Peritoneal Metastasis.低剂量顺铂和阿霉素的腹腔内加压气雾化疗（PIPAC）用于胃腹膜转移
J Gastrointest Surg. 2016 Feb;20(2):367-73. doi: 10.1007/s11605-015-2995-9. Epub 2015 Oct 28.
4
Pressurized intraperitoneal aerosol chemotherapy with oxaliplatin in colorectal peritoneal metastasis.奥沙利铂腹腔内加压雾化化疗用于结直肠癌腹膜转移
Colorectal Dis. 2016 Apr;18(4):364-71. doi: 10.1111/codi.13130.
5
Pressurized intraperitoneal aerosol chemotherapy (PIPAC): occupational health and safety aspects.腹腔内压力气溶胶化疗（PIPAC）：职业健康与安全方面。
Ann Surg Oncol. 2013 Oct;20(11):3504-11. doi: 10.1245/s10434-013-3039-x. Epub 2013 Jun 14.
6
Rationale and techniques of cytoreductive surgery and peritoneal chemohyperthermia.细胞减灭术和腹腔温热化疗的原理和技术。
World J Gastrointest Oncol. 2011 Dec 15;3(12):169-74. doi: 10.4251/wjgo.v3.i12.169.
7
Treatment of gastric cancer with peritoneal carcinomatosis by cytoreductive surgery and HIPEC: a systematic review of survival, mortality, and morbidity.腹腔热灌注化疗联合细胞减灭术治疗腹膜转移癌：一项生存、死亡率和发病率的系统评价。
J Surg Oncol. 2011 Nov 1;104(6):692-8. doi: 10.1002/jso.22017. Epub 2011 Jun 28.
8
Systematic review of intraperitoneal chemotherapy for gastric cancer.胃癌腹腔内化疗的系统评价。
Br J Surg. 2011 Sep;98(9):1225-35. doi: 10.1002/bjs.7586. Epub 2011 Jun 6.
9
Intraperitoneal therapy for peritoneal tumors: biophysics and clinical evidence.腹腔内治疗腹腔肿瘤：生物物理学和临床证据。
Nat Rev Clin Oncol. 2010 Feb;7(2):108-15. doi: 10.1038/nrclinonc.2009.217. Epub 2009 Dec 15.
Zotero 插件