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负载大黄素的介孔二氧化硅纳米颗粒SBA-15上调了金毛虫幼虫的抗氧化防御能力。

Mesoporous silica nanoparticles SBA-15 loaded with emodin upregulate the antioxidative defense of Euproctis chrysorrhoea (L.) larvae.

作者信息

Janković-Tomanić Milena, Todorović Dajana, Stanivuković Zoran, Perić Mataruga Vesna, Wessjohann Ludger A, Kaluđerović Goran N

机构信息

Department of Insect Physiology and Biochemistry, Institute for Biological Research "Siniša Stanković", University of Belgrade , Belgrade , Serbia.

Department of Integrated Protection of Forest Ecosystems, Faculty of Forestry, University of Banja Luka , Banja Luka , Bosnia and Herzegovina.

出版信息

Turk J Biol. 2017 Dec 18;41(6):935-942. doi: 10.3906/biy-1705-76. eCollection 2017.

Abstract

The study presented here aims to elucidate the effects of emodin (EO = 1,3,8-trihydroxy-6-methylanthraquinone) in its free form and when loaded into a mesoporous silica nanocarrier SBA-15 (→ SBA-15|EO) on the activities of the main antioxidative enzymes, superoxide dismutase, catalase, glutathione S-transferase, and glutathione reductase, in larvae of a polyphagous insect pest, the browntail moth Euproctis chrysorrhoea (L.). The results show that only SBA-15|EO upregulates the activities of the tested antioxidative enzymes. These results point to significant differences in the effectiveness of the compound in the free versus the loaded form.

摘要

本文所呈现的研究旨在阐明游离形式的大黄素(EO = 1,3,8 - 三羟基 - 6 - 甲基蒽醌)以及负载于介孔二氧化硅纳米载体SBA - 15(→ SBA - 15|EO)时,对多食性害虫棕尾毒蛾(Euproctis chrysorrhoea (L.))幼虫体内主要抗氧化酶超氧化物歧化酶、过氧化氢酶、谷胱甘肽S - 转移酶和谷胱甘肽还原酶活性的影响。结果表明,只有SBA - 15|EO能上调所测试抗氧化酶的活性。这些结果表明该化合物游离形式与负载形式的有效性存在显著差异。

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