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与阿哌沙班相关的非创伤性脾破裂。

Atraumatic splenic rupture associated with apixaban.

作者信息

Basnet Sijan, Mohanty Elan, Mir Izza, Dhital Rashmi, Koirala Ajay, Tachamo Niranjan

机构信息

Department of Medicine, Reading Hospital and Medical Center, West Reading, PA, USA.

出版信息

SAGE Open Med Case Rep. 2019 Feb 21;7:2050313X19832490. doi: 10.1177/2050313X19832490. eCollection 2019.

DOI:10.1177/2050313X19832490
PMID:30815265
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6385321/
Abstract

Apixaban is a direct oral anticoagulant that works by inhibiting factor Xa. It has been associated with adverse bleeding outcomes including atraumatic splenic rupture. We present the case of an 86-year-old man who presented with features of left upper abdominal pain and hemorrhagic shock found to have atraumatic splenic rupture and hemoperitoneum on imaging.

摘要

阿哌沙班是一种直接口服抗凝剂,通过抑制凝血因子Xa起作用。它与不良出血后果有关,包括非创伤性脾破裂。我们报告了一例86岁男性患者,其表现为左上腹疼痛和失血性休克,影像学检查发现有非创伤性脾破裂和腹腔积血。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/511a/6385321/fb027d40048d/10.1177_2050313X19832490-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/511a/6385321/fb027d40048d/10.1177_2050313X19832490-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/511a/6385321/fb027d40048d/10.1177_2050313X19832490-fig1.jpg

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Ir Med J. 2018 Aug 13;111(7):792.
2
Spontaneous splenic rupture due to rivaroxaban.利伐沙班所致自发性脾破裂
Drug Ther Bull. 2018 Nov;56(11):136-139. doi: 10.1136/dtb.2018.11.223237rep.
3
Spontaneous splenic rupture secondary to dabigatran: the last in a series of unfortunate events.继发于达比加群的自发性脾破裂:一连串不幸事件中的最后一件。
利伐沙班治疗患者的非创伤性脾破裂:一例报告及文献综述
Clin Case Rep. 2022 Nov 3;10(11):e6462. doi: 10.1002/ccr3.6462. eCollection 2022 Nov.
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Atraumatic Splenic Rupture on Direct Oral Anticoagulation.直接口服抗凝治疗时的非创伤性脾破裂
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A Spleen Complication After an Acute Myocardial Infarction.急性心肌梗死后的脾脏并发症
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Atraumatic Splenic Rupture in a Patient on Apixaban and Dual Antiplatelet Therapy.服用阿哌沙班和双联抗血小板治疗的患者发生非外伤性脾破裂。
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J Clin Med. 2020 Sep 15;9(9):2984. doi: 10.3390/jcm9092984.
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Atraumatic splenic rupture in a patient treated with apixaban: A case report.接受阿哌沙班治疗的患者发生非创伤性脾破裂:一例病例报告。
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