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肥胖在初产妇妊娠期高血压中的作用:伊朗沙德甘的一项病例对照研究。

Role of obesity in gestational hypertension in primigravidae women: A case control study in Shadegan, Iran.

作者信息

Moftakhar Leila, Solaymani-Dodaran Masoud, Cheraghian Bahman

机构信息

Department of Epidemiology, School of Health, Iran University of Medical Sciences, Tehran, Iran.

Minimally Invasive Surgery Research Center, Iran University of Medical Sciences, Tehran, Iran.

出版信息

Med J Islam Repub Iran. 2018 Oct 28;32:104. doi: 10.14196/mjiri.32.104. eCollection 2018.

Abstract

Gestational hypertension is a serious problem among pregnant women in Shadegan. This study was conducted to estimate the prevalence and risk factors of gestational hypertension in these women. In this study, the prevalence of gestational hypertension was estimated. Then, a case-control study was performed on 310 pregnant women with gestational hypertension and 930 healthy pregnant women in 2014. Multiple logistic regression was used to explore the possible risk factors. The analysis was repeated in a subgroup of primigravidae women to identify the risk factors that led to gestational hypertension. The prevalence of gestational hypertension among pregnant women in Shadegan was 9.6%. Moreover, multiple logistic regression of all pregnant women showed that obese pregnant women were 1.79 times (OR = 1.79; 95%CI= 1.19-2.71; p<0.005) more likely to have gestational hypertension. Overweight and obese primigravidae women were 2.13 (OR= 2.1; 95%CI= 1.031-4.34; p<0.041) and 4.8 (OR= 2.4; 95%CI= 1.13-5.16; p<0.022) times more likely to have gestational hypertension than women with normal BMI, respectively. Age, education, history of gestational hypertension, and type of residential area of the primigravidae women were also significant factors. BMI is the most important risk factor for gestational hypertension. More focus needs to be laid on this issue to raise awareness on the preservation of proper BMI before pregnancy, which can help decrease gestational hypertension.

摘要

妊娠高血压是沙德甘地区孕妇面临的一个严重问题。本研究旨在估计这些女性中妊娠高血压的患病率及风险因素。在本研究中,对妊娠高血压的患病率进行了估计。然后,2014年对310名患有妊娠高血压的孕妇和930名健康孕妇进行了病例对照研究。采用多因素logistic回归分析探讨可能的风险因素。在初产妇亚组中重复该分析以确定导致妊娠高血压的风险因素。沙德甘地区孕妇中妊娠高血压的患病率为9.6%。此外,对所有孕妇进行的多因素logistic回归分析显示,肥胖孕妇患妊娠高血压的可能性是正常孕妇的1.79倍(比值比=1.79;95%置信区间为1.19 - 2.71;p<0.005)。初产妇中超重和肥胖者患妊娠高血压的可能性分别是体重指数正常女性的2.13倍(比值比=2.1;95%置信区间为1.031 - 4.34;p<0.041)和4.8倍(比值比=2.4;95%置信区间为1.13 - 5.16;p<0.022)。初产妇的年龄、教育程度、妊娠高血压病史及居住地区类型也是重要因素。体重指数是妊娠高血压最重要的风险因素。需要更多关注这个问题,以提高对孕前保持适当体重指数的认识,这有助于降低妊娠高血压的发生率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c936/6387809/a85a970df1cc/mjiri-32-104-g001.jpg

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