视网膜静脉分支阻塞中的血氧测定法。

Retinal oximetry in branch retinal vein occlusion.

机构信息

Department of Ophthalmology, Kagawa University Faculty of Medicine, Miki, Japan.

Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.

出版信息

Acta Ophthalmol. 2019 Sep;97(6):e896-e901. doi: 10.1111/aos.14070. Epub 2019 Feb 28.

DOI:10.1111/aos.14070

PMID:30816643

Abstract

PURPOSE

To measure retinal oxygen saturation (SO ) in eyes with branch retinal vein occlusion (BRVO).

METHODS

Retinal oximetry was performed using the Oxymap T1 retinal oximeter in 50 eyes (50 patients) with resolved BRVO. SO was calculated in each major retinal artery and vein in four quadrants. The superior or inferior hemisphere with BRVO was categorized as the affected hemisphere and the other as the unaffected hemisphere.

RESULTS

Oxymap T1 allowed us to measure SO in major retinal vessels. Both arterial and venous SO in the affected hemisphere were significantly higher than those in the unaffected hemisphere. However, there was no significant difference in arteriovenous (A-V) difference in SO between the affected and unaffected hemispheres. Of the 50 included eyes, 32 had non-ischemic BRVO and 18 had ischemic BRVO. In the affected hemisphere, arterial SO was significantly higher in ischemic BRVO (106.9 ± 8.8%) than in non-ischemic BRVO (101.3 ± 9.2%, p = 0.044). There were no significant differences in venous SO between non-ischemic and ischemic BRVO. Consequently, the A-V difference in SO was significantly higher in ischemic BRVO (51.9 ± 13.9%) than in non-ischemic BRVO (43.4 ± 11.5%, p = 0.028). In multiple regression analysis, the type of perfusion (non-ischemic or ischemic) had associations with arterial SO (β = 0.365, p = 0.013) and with A-V differences in SO in the affected hemisphere (β = 0.406, p = 0.006).

CONCLUSION

In ischemic BRVO, arterial SO and the A-V difference in SO in the affected hemisphere were significantly higher than in non-ischemic BRVO.

摘要

目的

测量已缓解的分支视网膜静脉阻塞（BRVO）眼中的视网膜氧饱和度（SO ）。

方法

使用 Oxymap T1 视网膜血氧计对 50 只眼（50 例患者）进行视网膜血氧测量。在四个象限中计算每个主要视网膜动脉和静脉中的 SO 。有 BRVO 的上或下半球归类为受影响的半球，另一个为未受影响的半球。

结果

Oxymap T1 允许我们测量主要视网膜血管中的 SO 。受影响半球的动脉和静脉 SO 均明显高于未受影响半球。然而，受影响和未受影响半球之间的 SO 动静脉（A-V）差异没有显著差异。在纳入的 50 只眼中，有 32 只患有非缺血性 BRVO，18 只患有缺血性 BRVO。在受影响的半球中，缺血性 BRVO 的动脉 SO （106.9±8.8%）明显高于非缺血性 BRVO （101.3±9.2%，p=0.044）。非缺血性和缺血性 BRVO 之间的静脉 SO 无显著差异。因此，缺血性 BRVO 的 SO 动静脉差异（51.9±13.9%）明显高于非缺血性 BRVO （43.4±11.5%，p=0.028）。在多元回归分析中，灌注类型（非缺血性或缺血性）与动脉 SO （β=0.365，p=0.013）和受影响半球中 SO 的 A-V 差异（β=0.406，p=0.006）有关。