La Paz University Hospital, Psychiatry, Paseo de la Castellana 261, 28036 Madrid, Spain.
La Paz University Hospital, Madrid, Spain.
J Clin Psychiatry. 2019 Feb 26;80(2):18m12416. doi: 10.4088/JCP.18m12416.
To determine the comparative effectiveness of 3 real-practice preventive programs aimed at lowering the relapse risk following a suicide attempt: a single priority appointment with an outpatient psychiatrist, an enhanced contact intervention, and an individual psychotherapy program.
This observational study was conducted in a sample of 1,492 suicide attempters from 3 catchment areas in Madrid, Spain, between 2013 and 2017. Relapse was defined as an emergency department return after a new attempt within a 1-year follow-up. Kaplan-Meier survival functions were obtained by intervention, and Cox proportional hazard regression models were used to estimate unadjusted and adjusted risks of relapse by intervention. Sex- and age-stratified analyses were also conducted. Covariates were age, sex, history of suicide attempts, history of psychiatric disorders, main ICD-10 psychiatric diagnostic groups, medical comorbidities, and family support.
A total of 133 subjects (8.9%) relapsed. The psychotherapy group had a lower presence of known risk factors for suicide attempt. Individual psychotherapy and enhanced contact were more effective than a single priority appointment at reducing suicide reattempt, with a 40% lower relapse risk in adjusted models. Results did not differ after sex and age stratification.
In a naturalistic clinical setting, patients exposed to individual psychotherapy or an enhanced contact intervention had a similar, lower relapse risk than the single priority appointment group.
比较 3 种真实实践预防项目在降低自杀未遂后复发风险方面的效果,这 3 种项目分别为:与门诊精神科医生的单次优先预约、强化接触干预和个体心理治疗方案。
本观察性研究纳入了来自西班牙马德里 3 个地区的 1492 名自杀未遂者,研究时间为 2013 年至 2017 年。复发定义为在 1 年随访内新的尝试后返回急诊室。通过干预获得 Kaplan-Meier 生存函数,并使用 Cox 比例风险回归模型估计干预的未调整和调整后的复发风险。还进行了按性别和年龄分层的分析。协变量为年龄、性别、自杀未遂史、精神障碍史、主要 ICD-10 精神科诊断组别、合并症和家庭支持。
共有 133 名受试者(8.9%)复发。心理治疗组自杀未遂的已知危险因素发生率较低。个体心理治疗和强化接触干预比单次优先预约更能有效降低自杀再尝试,调整模型显示复发风险降低了 40%。在性别和年龄分层后,结果没有差异。
在自然临床环境中,接受个体心理治疗或强化接触干预的患者与单次优先预约组相比,复发风险相似且更低。