From the Department of Clinical and Molecular Medicine, Sapienza University, Pathology Unit, Sant'Andrea Hospital.
Plast Reconstr Surg. 2019 Mar;143(3S A Review of Breast Implant-Associated Anaplastic Large Cell Lymphoma):15S-22S. doi: 10.1097/PRS.0000000000005565.
Late onset of fluid collection surrounding breast implants may represent a serious issue when considering the possibility of breast implant-associated anaplastic large cell lymphoma, a newly recognized type of T-cell malignancy. However, many other factors, including trauma and infections, may be implicated in the formation of non-neoplastic periprosthetic delayed effusions. An appropriate management of late seromas, consisting of ultrasound-guided fluid drainage, cultures, cytology, and immunocytochemical and T-cell clonality studies, should be performed to achieve a correct and prompt diagnosis of breast implant-associated anaplastic large cell lymphoma. Criticisms in the diagnosis of late peri-implant effusions are here discussed in detail.
当考虑到乳房植入物相关间变性大细胞淋巴瘤（一种新认识的 T 细胞恶性肿瘤）的可能性时，乳房植入物周围迟发性积液的出现可能代表一个严重的问题。然而，许多其他因素，包括创伤和感染，可能与非肿瘤性假体周围延迟性积液的形成有关。适当的迟发性血清肿管理，包括超声引导下的液体引流、培养、细胞学以及免疫细胞化学和 T 细胞克隆性研究，应进行以实现对乳房植入物相关间变性大细胞淋巴瘤的正确和及时诊断。本文详细讨论了对迟发性假体周围积液的诊断提出的批评意见。
