Bušová Andrea, Dorko Erik, Feketeová Eva, Rimárová Kvetoslava, Diabelková Jana, Rovenská Tímea, Csank Tomáš
Department of Public Health and Hygiene, Faculty of Medicine, Pavol Jozef Safarik University in Kosice, Kosice, Slovak Republic.
Department of Neurology, Faculty of Medicine, Pavol Jozef Safarik University in Kosice and Louis Pasteur University Hospital, Kosice, Slovak Republic.
Cent Eur J Public Health. 2018 Dec;26 Suppl:S61-S66. doi: 10.21101/cejph.a5274.
The aim of the presented cross-sectional seroepidemiological study was to determine the current presence of antibodies against B. burgdorferi s.l. in the groups of Slovak population, and to identify potential risk factors to Lyme borreliosis.
A group of 261 adults (patients from the Neurological Clinic with possible symptoms of LB and healthy persons with possible working exposure to tick bite: gardeners and soldiers working in afforested areas) were examined in order to assess the seroprevalence of anti-Borrelia antibodies. Sera were screened by commercial enzyme-linked immunosorbent assay (ELISA). The respondents completed questionnaires with general demographic, epidemiological and clinical data.
We detected 17.2% presence of positive IgG and 5.7% presence of positive IgM antibodies in all investigated groups. Our results confirmed that the following risk factors such as age and gender are significantly associated with the presence of positive specific antibodies against investigated disease.
The results of seroprevalence obtained in the present study confirm the possibility of infection with B. burgdorferi among respondents exposed to contact with ticks.
本横断面血清流行病学研究的目的是确定斯洛伐克人群中抗伯氏疏螺旋体复合群抗体的当前存在情况，并确定莱姆病的潜在危险因素。
对一组261名成年人（来自神经科诊所、可能有莱姆病症状的患者以及可能因工作接触蜱叮咬的健康人：园丁和在林区工作的士兵）进行检查，以评估抗伯氏疏螺旋体抗体的血清阳性率。血清通过商业酶联免疫吸附测定（ELISA）进行筛查。受访者填写了包含一般人口统计学、流行病学和临床数据的问卷。
在所有调查组中，我们检测到17.2%的IgG阳性和5.7%的IgM阳性抗体。我们的结果证实，年龄和性别等以下危险因素与针对所研究疾病的特异性阳性抗体的存在显著相关。
本研究获得的血清阳性率结果证实了接触蜱的受访者感染伯氏疏螺旋体的可能性。
