Francomano F, De Remigis P L, Rossi M, Cotellese R, Capone F, Ucchino S, Mazzoni L, Puglielli L, Napolitano A M, Sensi S
Minerva Med. 1986 Feb 28;77(7-8):215-22.
Toxic goitre often referred to in the literature as "autonomous" adenoma or nodule actually signifies a number of different pathologies that are characterised by autonomy and hyperfunction so that it is now thought more appropriate to call it an autonomous follicle. Clinical features and the hormone profile suggest the diagnosis which is confirmed by scintiscan with curve as well as dynamic inhibition and stimulation tests using TRH, procedures that reveal both latent hyperfunction and autonomy. The most common current therapeutic approach is surgical since this provides a complete cure while leaving the surrounding thyroid tissue undisturbed.
毒性甲状腺肿在文献中常被称为“自主性”腺瘤或结节，实际上代表了多种不同的病理情况，其特征为自主性和功能亢进，因此现在认为将其称为自主性滤泡更为合适。临床特征和激素谱提示诊断，通过闪烁扫描曲线以及使用促甲状腺激素释放激素（TRH）的动态抑制和刺激试验得以证实，这些检查可揭示潜在的功能亢进和自主性。目前最常用的治疗方法是手术，因为手术能实现完全治愈，同时不干扰周围的甲状腺组织。
