McGill University, Montreal, Quebec, Canada.
J Aging Health. 2020 Jun/Jul;32(5-6):462-471. doi: 10.1177/0898264319831513. Epub 2019 Feb 28.
This study examined genetic roots of later life social integration, and their confounding of this social factor's health linkages. Data were from the 2010 wave of the Health and Retirement Study. Two dimensions of integration were examined: with one's "stakeholder" network of family and friends and with the community. Genetic measures included polygenic scores for extraversion and educational attainment. Ties to one's stakeholder network had no genetic associations. The extraversion polygenic score was linked to community integration among Blacks as well as Whites. Among the latter, the same was true of one's genetic propensity for educational attainment. Although this score also influenced self-rated health, neither confounded associations of social integration with this indicator. Later life social integration seems influenced by genetically rooted propensities for both sociability and human capital accumulation. Health linkages of integration, however, may not reflect mutual dependencies on the same genetic substrates.
本研究考察了晚年社会融合的遗传根源，以及这些遗传因素对社会因素与健康关联的混淆。数据来自 2010 年健康与退休研究的调查。本研究考察了两个融合维度：与“利益相关者”的家庭和朋友网络的融合，以及与社区的融合。遗传测量包括外向性和教育程度的多基因评分。与利益相关者网络的联系没有遗传关联。外向性多基因评分与黑人和白人的社区融合有关。在后者中，一个人的遗传教育程度倾向也同样如此。尽管这一评分也影响了自我评估的健康状况，但它并没有混淆社会融合与这一指标的关联。晚年社会融合似乎受到社交和人力资本积累的遗传倾向的影响。然而，社会融合的健康关联可能并不反映对同一遗传基础的相互依赖。
