Smith Craig R, Gardner Jeffrey T, Vaughn Lexie H, Kelly Robert J, Whipple Oliver C
Am Surg. 2019 Feb 1;85(2):173-176.
Gastroesophageal reflux disease (GERD) is significantly more prevalent in obese patients. Nissen fundoplication alleviates symptoms in those refractory to dietary changes and optimal medical management. The need for concomitant treatment of GERD and obesity is becoming more prevalent. The objective of this study was to determine whether Nissen-preserving laparoscopic sleeve gastrectomy (SG) is a safe and effective weight loss option for patients with pre-existing Nissen fundoplication. The study was conducted at the Hospital Corporation of America, Memorial Health, Savannah, Georgia, academic institution. We retrospectively reviewed five patients who underwent laparoscopic Nissen-preserving SG between 2011 and 2017. We compared pre- and postoperative subjective GERD symptoms, occurrence of any immediate postoperative complications, change in BMI, and excess weight loss. Of the five patients, four were female and one was male. The mean age was 50.6 years. The mean preoperative BMI was 44.8 ± 5.4, one-month postoperative BMI was 41.2 ± 6.1 ( < 0.001), and six-month postoperative BMI was 37.5 ± 8.1 ( < 0.009), with mean excess weight loss at six months of 33.9 ± 23 per cent. There were no immediate postoperative complications. Subjective GERD symptoms were unchanged in two patients and improved in the other three. We demonstrate the early feasibility of Nissen-preserving SG for surgical weight loss in patients with existing Nissen fundoplication. Although our results are early, we feel encouraged by mean excess weight loss to date and control of GERD symptoms.
胃食管反流病(GERD)在肥胖患者中更为普遍。nissen胃底折叠术可缓解那些对饮食改变和最佳药物治疗无效的患者的症状。同时治疗GERD和肥胖症的需求日益普遍。本研究的目的是确定保留nissen的腹腔镜袖状胃切除术(SG)对于已行nissen胃底折叠术的患者是否是一种安全有效的减肥选择。该研究在佐治亚州萨凡纳市的美国医院公司纪念健康学术机构进行。我们回顾性分析了2011年至2017年间接受腹腔镜保留nissen SG手术的5例患者。我们比较了术前和术后的主观GERD症状、术后即刻并发症的发生情况、BMI的变化以及超重减轻情况。5例患者中,4例为女性,1例为男性。平均年龄为50.6岁。术前平均BMI为44.8±5.4,术后1个月BMI为41.2±6.1(<0.001),术后6个月BMI为37.5±8.1(<0.009),6个月时平均超重减轻33.9±23%。术后无即刻并发症。2例患者的主观GERD症状未改变,另外3例有所改善。我们证明了保留nissen的SG对于已有nissen胃底折叠术的患者进行手术减肥的早期可行性。虽然我们的结果尚属早期,但迄今为止的平均超重减轻情况和GERD症状控制情况让我们感到鼓舞。