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腹腔镜下胃袖套切除术并发慢性瘘管:转为 Roux-en-Y 胃旁路术。

Chronic Fistula Post Laparoscopic Nissen Sleeve Gastrectomy: Conversion to Roux-en-Y Gastric Bypass.

机构信息

Division of Digestive Surgery and Liver Transplantation, Nice University Hospital, Nice, France.

Department of Medical and Surgical Sciences and Translational Medicine, Sant'Andrea University Hospital, Sapienza University, via di Grottarossa 1035-1039, Rome, Italy.

出版信息

Obes Surg. 2019 Oct;29(10):3414-3415. doi: 10.1007/s11695-019-04080-3.

Abstract

BACKGROUND

Sleeve gastrectomy (SG) is the most frequently performed bariatric intervention worldwide, and obese patients have a higher risk of developing reflux symptoms compared with the general population [1, 2]. One of the controversies of SG is to perform it in patients with gastroesophageal reflux disease (GERD). Some studies have shown that SG may exacerbate GERD symptoms or even increase the risk of "de novo" postoperative GERD [3, 4]. Laparoscopic Nissen fundoplication is an effective treatment for patients with severe GERD. In order to avoid the Roux-en-Y gastric bypass (RYGB), some authors combined the SG with the Nissen fundoplication in morbid obese patients with GERD [5]. As after SG, postoperative gastric fistula may occur after Nissen SG. Persistent fistula after Nissen SG may be treated by conversion to RYGB.

METHODS

We present the case of a 35-year-old woman with long-standing morbid obesity, who presented to our institution seeking management options for her postoperative fistula. In August 2018, she underwent a laparoscopic Nissen SG in another institution. Her initial weight was 107 kg, height 172 cm, and body mass index (BMI) 36.27 kg/m. At the 7th postoperative day, she complained of severe abdominal pain and fever. A computed tomography (CT) scan was performed showing a massive supra-mesocolic pneumoperitoneum. An explorative laparoscopy was performed with evidence of a generalized peritonitis without identification of the orifice of the leak. Peritoneal lavage of the abdominal cavity was done and the patient was transferred to our institution. An upper gastrointestinal endoscopy was performed with evidence of a fistula on the gastric longitudinal staple line (8 mm in diameter), and a stenosis of about 15 mm on the distal gastric tube. A double pig-tail was placed. After 14 days, the patient underwent a gastric pneumatic dilatation of the stenosis placed at the antro-fundic region, without complications. Three months later, the fistula was persistent; therefore, after a careful nutritional and psychological evaluation and discussion with the patient, we decided to perform a conversion to a RYGB. The valve of the Nissen fundoplication was identified and divided using a stapler. The orifice of the fistula was identified. Resection of this valve, including the orifice of the fistula and the gastric tube, was done using a blue-load stapler ECHELON FLEX™ GST (Ethicon Endo-Surgery, USA) while creating the new gastric pouch. Then, we performed a Roux-en-Y gastric bypass with a 150-cm alimentary limb and a 50-cm biliary limb. The Petersen and the mesenteric defects were closed.

RESULTS

The blood loss was less than 100 cc and the operative time was 240 min. The postoperative period was smooth and uneventful; the patient was started on liquid diet on the second postoperative day and discharged at day 8. At 1 month postoperatively, the patient has lost 16 kg and the %EWL was 36.53%, %TWL 14.95% with a BMI of 30.84 kg/m. At 6 months postoperatively, the patient lost 24 kg, with a BMI at 26 kg/m. She does not complain of GERD, no vomiting, no abdominal pain, and no diarrhea.

CONCLUSIONS

In cases of fistulas after Nissen SG, the surgery becomes more tedious and difficult. Conversion to RYGB seems a feasible and effective option to treat chronic fistula after Nissen SG.

摘要

背景

袖状胃切除术(SG)是全球最常进行的减重手术,肥胖患者发生反流症状的风险高于普通人群[1,2]。SG 的争议之一是在胃食管反流病(GERD)患者中进行。一些研究表明,SG 可能会加重 GERD 症状,甚至增加“新发”术后 GERD 的风险[3,4]。腹腔镜 Nissen 胃底折叠术是治疗严重 GERD 的有效方法。为了避免 Roux-en-Y 胃旁路术(RYGB),一些作者将 SG 与 Nissen 胃底折叠术联合用于患有 GERD 的病态肥胖患者[5]。由于 SG 后可能会发生胃食管瘘,因此在 Nissen SG 后可能会发生术后胃瘘。Nissen SG 后持续存在瘘管可通过转换为 RYGB 来治疗。

方法

我们报告了一位 35 岁的长期病态肥胖女性的病例,她到我院寻求术后瘘管的治疗方案。2018 年 8 月,她在另一家机构接受了腹腔镜 Nissen SG。她的初始体重为 107kg,身高 172cm,体重指数(BMI)为 36.27kg/m2。术后第 7 天,她主诉严重腹痛和发热。进行了计算机断层扫描(CT)扫描,显示巨大的膈上气腹。进行了腹腔镜探查,发现全腹膜炎,但无法确定漏口。进行了腹腔灌洗,患者被转至我院。进行了上消化道内镜检查,发现胃纵向订书钉线上有瘘管(直径 8mm),远端胃管有 15mm 左右的狭窄。放置了双猪尾管。14 天后,患者在贲门-胃底部区域进行了胃气动扩张狭窄,无并发症。3 个月后,瘘管仍然存在;因此,在对患者进行了仔细的营养和心理评估,并与患者进行了讨论后,我们决定进行 RYGB 转换。使用吻合器识别并分割 Nissen 胃底折叠术的瓣。确定瘘口。使用 ECHELON FLEX™ GST 蓝色载入吻合器(Ethicon Endo-Surgery,美国)切除包括瘘口和胃管在内的瓣,同时创建新的胃袋。然后,我们进行了 Roux-en-Y 胃旁路术,其中 150cm 的食物肢和 50cm 的胆肢。关闭 Petersen 和肠系膜缺损。

结果

出血量少于 100cc,手术时间为 240 分钟。术后恢复顺利,患者在术后第 2 天开始进流食,并于第 8 天出院。术后 1 个月,患者体重减轻 16kg,体质量减轻率(EWL)为 36.53%,总体重量减轻率(TWL)为 14.95%,BMI 为 30.84kg/m2。术后 6 个月,患者体重减轻 24kg,BMI 为 26kg/m2。她没有抱怨 GERD、呕吐、腹痛或腹泻。

结论

在 Nissen SG 后发生瘘管的情况下,手术变得更加繁琐和困难。转换为 RYGB 似乎是治疗 Nissen SG 后慢性瘘管的一种可行且有效的选择。

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