Departamento de Ciências Animais, Universidade Federal Rural do Semi-Árido, UFERSA, Av. Francisco Mota, 572 -Bairro Costa e Silva, Mossoró, RN, CEP: 59.625-900, Brazil.
Departamento de Morfologia, Universidade Federal do Rio Grande do Norte, Natal, RN, Brazil.
Biotechnol Lett. 2019 May;41(4-5):503-510. doi: 10.1007/s10529-019-02657-7. Epub 2019 Feb 28.
To evaluate the effects of the surface modification of 316L stainless steel (SS) by low-temperature plasma nitriding on endothelial cells for stent applications.
X-ray diffraction (XRD) confirmed the incorporation of nitrogen into the treated steel. The surface treatment significantly increased SS roughness and hydrophilic characteristics. After 4 h the cells adhered to the nitride surfaces and formed clusters. During the 24 h incubation period, cell viability on the nitrided surface was higher compared to the polished surface. Nitriding reduced late apoptosis of rabbit aorta endothelial cell (RAEC) on the SS surface.
Low temperature plasma nitriding improved the biocompatible of stainless steel for use in stents.
评估低温等离子体氮化处理 316L 不锈钢（SS）表面对用于支架的内皮细胞的影响。
X 射线衍射（XRD）证实了氮被引入处理后的钢中。表面处理显著提高了 SS 的粗糙度和亲水性。4 小时后，细胞附着在氮化物表面并形成簇。在 24 小时孵育期间，氮化物表面上的细胞活力高于抛光表面。氮化减少了 SS 表面兔主动脉内皮细胞（RAEC）的晚期凋亡。
低温等离子体氮化提高了不锈钢在支架中的生物相容性。
