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应对提高粮食作物营养品质和食品安全的挑战:利用蛋白质组学和相关组学技术。

Meeting the challenge of developing food crops with improved nutritional quality and food safety: leveraging proteomics and related omics techniques.

机构信息

Department of Plant Pathology, North Dakota State University, Fargo, ND, USA.

Department of Botany, Gargi College, New Delhi, India.

出版信息

Biotechnol Lett. 2019 May;41(4-5):471-481. doi: 10.1007/s10529-019-02655-9. Epub 2019 Feb 28.

Abstract

Eliminating malnutrition remains an imminent priority in our efforts to achieve food security and providing adequate calories, proteins, and micronutrients to the growing world population. Malnutrition may be attributed to socio-economic factors (poverty and limited accessibility to nutritional food), dietary preferences, inherent nutrient profiles of traditional food crops, and to a combination of all such factors. Modern advancements in "omics" technology have made it possible to reliably predict, diagnose, and suggest ways to remedy the low protein content and bioavailability of key micronutrients in food crops. In this review, we briefly describe how proteomics techniques can potentially be used for improving the nutrient profile of major crops, through high throughput multiplexed assays. Food safety is another important issue where proteomics and related platforms can offer solution for absolute quantitation of food allergens and mycotoxins present in the plant-based food. The purpose of the present review is to discuss the proteomic-based strategies in food crops to meet the challenges of overcoming malnutrition throughout the world.

摘要

消除营养不良仍然是我们实现粮食安全努力的当务之急,为不断增长的世界人口提供足够的热量、蛋白质和微量营养素。营养不良可能归因于社会经济因素(贫困和获得营养食品的机会有限)、饮食偏好、传统粮食作物固有的营养成分,以及所有这些因素的综合作用。“组学”技术的现代进步使得可靠地预测、诊断和提出改善粮食作物中关键微量营养素的低蛋白质含量和生物利用度的方法成为可能。在这篇综述中,我们简要描述了蛋白质组学技术如何通过高通量多重分析潜在地用于改善主要作物的营养成分。食品安全是另一个重要问题,蛋白质组学和相关平台可以为植物性食品中存在的食物过敏原和霉菌毒素的绝对定量提供解决方案。本综述的目的是讨论基于蛋白质组学的策略在粮食作物中的应用,以应对在全球范围内克服营养不良的挑战。

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