Sjöström Rita, Söderström Lars, Klockmo Carolina, Patrician Alexander, Sandström Thomas, Björklund Glenn, Hanstock Helen, Stenfors Nikolai
a Department of Community Medicine and Rehabilitation , Umeå University , Umeå , Sweden.
b Unit of Research, Education and Development , Östersund Hospital , Östersund , Sweden.
Int J Circumpolar Health. 2019 Dec;78(1):1583528. doi: 10.1080/22423982.2019.1583528.
Exposure to cold air is associated with increased morbidity and mortality in the general population. It is difficult to study the effects of whole-body exposure to cold air under controlled conditions in real life.
The aim of this study was to (1) explore and describe the experience of symptoms in humans during experimental and controlled exposures to cold air, by using controlled environmental chamber exposures and qualitative methodology, and to (2) categorise the symptoms.
The study used a randomised, double blind design, in which 34 subjects undertook rest and moderate-intensity exercise in an environmental chamber set to two or three different temperatures (0, -10, and -17°C) on separate occasions. During the chamber exposures, subjects were interviewed. Qualitative content analysis was selected as the method of analysis.
Subjects reported 50 distinct symptoms during the exposures. The symptoms were grouped into ten sub-categories and two major categories; airway versus whole-body symptoms.
We have identified a broad range of symptoms in humans undertaking rest and moderate-intensity exercise at sub-zero temperatures. The symptoms and their categories may well be used to more extensively and quantitatively map cold-induced morbidity.
暴露于冷空气与普通人群发病率和死亡率的增加有关。在现实生活中，很难在可控条件下研究全身暴露于冷空气的影响。
本研究的目的是：（1）通过使用可控环境舱暴露和定性方法，探索并描述人体在实验性和可控性冷空气暴露期间的症状体验；（2）对症状进行分类。
本研究采用随机双盲设计，34名受试者分别在设置为两个或三个不同温度（0、-10和-17°C）的环境舱中进行休息和中等强度运动。在环境舱暴露期间，对受试者进行访谈。选择定性内容分析法作为分析方法。
受试者在暴露期间报告了50种不同的症状。这些症状被分为十个子类别和两个主要类别；气道症状与全身症状。
我们已经确定了在零下温度下进行休息和中等强度运动的人体中广泛的症状。这些症状及其类别很可能用于更广泛、定量地描绘寒冷诱发的发病率。
