Ambrose A, Cefalo R C, Bowes W A
Am J Obstet Gynecol. 1986 Mar;154(3):667-74. doi: 10.1016/0002-9378(86)90627-7.
Isovolemic exchange transfusion in the fetal lamb in utero was performed with the use of Fluosol-DA (20%), a perfluorochemical erythrocyte substitute. With maternal hyperoxygenation, a physiologic PO2 was maintained in the fetal lambs, although the total fetal oxygen content decreased as the hematocrit dropped. Because of the oxygen-carrying properties of the perfluorochemical emulsion, the fraction of fetal oxygen carried in the dissolved state increased significantly when compared with that in controls that received saline solution.
使用全氟化学红细胞替代物氟碳化合物乳剂（20%）对子宫内的胎羊进行等容交换输血。在母体进行高氧合时，尽管随着血细胞比容下降胎儿总氧含量降低，但胎羊的生理氧分压得以维持。由于全氟化学乳剂的携氧特性，与接受盐溶液的对照组相比，以溶解状态携带的胎儿氧分数显著增加。
