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在中国青少年的大样本中,压力性生活事件、失眠与自杀意念。

Stressful life events, insomnia and suicidality in a large sample of Chinese adolescents.

机构信息

Department of Epidemiology, Shandong University School of Public Health, Jinan 250012, China; Shandong University Center for Suicide Prevention and Research, No.44, Wenhuaxi Rd, Lixia Dist, Jinan 250012, China.

Department of Epidemiology, Shandong University School of Public Health, Jinan 250012, China; Shandong University Center for Suicide Prevention and Research, No.44, Wenhuaxi Rd, Lixia Dist, Jinan 250012, China; School of Psychology, South China Normal University, Shipai, Guangzhou 510631, China; The University of Tennessee Health Science Center, Memphis, TN 38163, USA.

出版信息

J Affect Disord. 2019 Apr 15;249:404-409. doi: 10.1016/j.jad.2019.02.047. Epub 2019 Feb 18.

Abstract

AIMS

This study aimed to examine the associations between stressful life events, insomnia, and suicidality including suicidal ideation (SI), suicide plan (SP) and suicide attempt (SA) in a large sample of Chinese adolescents.

METHODS

A total of 11,831 adolescents who participated in the baseline survey of Shandong Adolescent Behavior and Health Cohort were included for the analysis. Participants were sampled from 8 middle/high schools in 3 counties of Shandong, China. Participants completed a structured behavior and health questionnaire, including suicidality, demographics, depression/anxiety, stressful life events (SLEs), and insomnia in November-December 2015. A series of logistic regression models and mediation analyses were performed to examine the associations between SLEs, insomnia and suicidality.

RESULTS

The prevalence rates of overall suicidality, SI, SP and SA in the last year were 13.1%, 12.5%, 3.3%, and 1.5%, respectively. SLEs were significantly associated with overall suicidality, SI, and SP. Insomnia was an independent risk factor of suicidality and a mediator of the association between SLEs and suicidality. The total effect of SLEs on overall suicidality was 0.597 (95%CI: 0.534-0.661), including 0.457 (95%CI: 0.391-0.523) for direct effect and 0.158 (95%CI: 0.138-0.178) for indirect effect. Insomnia also mediated the associations of SLEs with SI, SP and SA, respectively.

LIMITATIONS

Causal relationship could not be concluded because this study is cross-sectional.

CONCLUSIONS

Stressful life events and insomnia are directly associated with suicidality in adolescents. The association between SLEs and suicidality is partially mediated by insomnia.

摘要

目的

本研究旨在探讨在中国青少年这一大样本中,压力性生活事件、失眠与自杀意念(SI)、自杀计划(SP)和自杀企图(SA)等自杀相关行为之间的关联。

方法

本研究共纳入了 11831 名参与山东青少年行为与健康队列研究基线调查的青少年。这些参与者来自中国山东省 3 个县的 8 所中学/高中。参与者于 2015 年 11 月至 12 月完成了一份包括自杀意念、人口统计学、抑郁/焦虑、压力性生活事件(SLEs)和失眠等内容的结构化行为和健康问卷。我们采用一系列逻辑回归模型和中介分析来检验 SLEs、失眠与自杀相关行为之间的关联。

结果

在过去一年中,整体自杀意念、SI、SP 和 SA 的发生率分别为 13.1%、12.5%、3.3%和 1.5%。SLEs 与整体自杀意念、SI 和 SP 显著相关。失眠是自杀意念的独立危险因素,也是 SLEs 与自杀意念之间关联的中介因素。SLEs 对整体自杀意念的总效应为 0.597(95%CI:0.534-0.661),其中 0.457(95%CI:0.391-0.523)为直接效应,0.158(95%CI:0.138-0.178)为间接效应。失眠也分别介导了 SLEs 与 SI、SP 和 SA 的关联。

局限性

由于本研究为横断面研究,因此无法得出因果关系。

结论

压力性生活事件和失眠与青少年的自杀意念直接相关。SLEs 与自杀意念的关联部分是通过失眠来介导的。

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