[急性淋巴细胞白血病患儿的间质性肺炎。诱导化疗期间用喷他脒预防（作者译）]
[Interstitial pneumonia in children with acute lymphoblastic leukemia. prophylaxis with pentamidine during induction chemotherapy (author's transl)].
作者信息
Klemm T, von Lengerke H J, Sieper J, Riehm H
出版信息
Radiologe. 1978 Jun;18(6):213-7.
PMID:308237
Abstract
The influence of pentamidine prophylaxis on incidence and degree of interstitial pneumonia (IP) during a standardized induction chemotherapy in 100 children with acute lymphoblastic leukemia has been investigated. For radiologic evaluation we established three stages of IP. With pentamidine prophylaxis the incidence of IP was reduced from 48% to 9%. In addition, there was a significant reduction of severe or lethal courses.
摘要
研究了喷他脒预防对100例急性淋巴细胞白血病儿童在标准化诱导化疗期间间质性肺炎（IP）发病率和严重程度的影响。为进行放射学评估，我们确定了IP的三个阶段。采用喷他脒预防后，IP的发病率从48%降至9%。此外，严重或致命病程也显著减少。
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