大鼠发育过程中2-14C-甲羟戊酸的氧化

Biol Neonate. 1986;49(3):168-71. doi: 10.1159/000242527.

In vivo oxidation of 2-14C-mevalonate is very low in 1- to 3-day-old rats and then rises to adult levels. Kidney slices oxidize mevalonate at an equal rate during development. However, at the time of weaning the rate is transiently increased in male rats only.

在1至3日龄的大鼠体内，2-14C-甲羟戊酸的氧化作用非常低，随后升至成年水平。在发育过程中，肾切片氧化甲羟戊酸的速率保持一致。然而，仅在雄性大鼠断奶时，该速率会短暂增加。