University of Washington School of Medicine and Seattle Children's Hospital, Seattle, WA.
University of Washington School of Medicine and Seattle Children's Hospital, Seattle, WA.
J Am Acad Child Adolesc Psychiatry. 2019 Dec;58(12):1157-1164. doi: 10.1016/j.jaac.2019.02.011. Epub 2019 Feb 27.
Despite advances in evidence-based treatments for youth depression in recent decades, overall treatment effects are modest at best, with 30% to 50% of youth being nonresponders. Practice parameters consistently recommend systematic assessment and routine monitoring of depressive symptoms, or measurement-based care (MBC), to enhance youth depression treatment. However, the literature offers few guidelines on how to use assessment results to inform care decisions or to detect real and clinically meaningful change. Thus the current study produced reliable change indices (RCIs) per Jacobson and Truax for two commonly used standardized assessments of youth depression (ie, Patient Health Questionnaire-9 items, Modified for Adolescents [PHQ-9A], the Short Moods and Feelings Questionnaire [SMFQ]).
The study sample (N = 1,738) consisted of youths 6 to 18 years old seen in a child and adolescent psychiatry clinic of a regional pediatric medical center who completed at least one of the target depression measures. We examined the factor structure and internal reliability for the PHQ-9A, and calculated RCIs for patients with a depression-related diagnosis for both measures.
Analyses confirmed a one-factor solution and adequate internal consistency (α = .86) for the PHQ-9A. All measures yielded acceptable test-retest reliabilities (r > 0.75) and RCIs that equate to clinical practice recommendations of using reliable changes scores of 7, 6, and 8 for the PHQ-9A, the SMFQ-Child Report, and the SMFQ-Parent Report, respectively.
Psychometric validation of the PHQ-9A and these RCIs are timely and significant contributions to the treatment of youth depression, by facilitating effective use of MBC-a critical evidence-based strategy for improving treatment outcomes.
尽管近几十年来针对青少年抑郁症的循证治疗取得了进展,但总体治疗效果充其量也只是适度的,有 30%至 50%的青少年对此没有反应。实践参数一直建议对抑郁症状进行系统评估和常规监测,或进行基于测量的护理(MBC),以增强青少年抑郁症的治疗效果。然而,文献中几乎没有关于如何使用评估结果来为护理决策提供信息或检测真实和具有临床意义的变化的指导方针。因此,本研究为两种常用的青少年抑郁症标准化评估工具(即,患者健康问卷-9 项,青少年修订版[PHQ-9A],短情绪和感觉问卷[SMFQ])生成了雅各布森和特鲁克斯的可靠变化指数(RCI)。
研究样本(N=1738)由在区域儿科医疗中心的儿童和青少年精神病学诊所就诊的 6 至 18 岁的青少年组成,他们至少完成了一项目标抑郁测量。我们检查了 PHQ-9A 的因子结构和内部信度,并为两种测量方法计算了具有与抑郁相关诊断的患者的 RCI。
分析结果证实了 PHQ-9A 的单因素解决方案和足够的内部一致性(α=0.86)。所有测量方法均产生了可接受的重测信度(r>0.75)和 RCI,这些 RCI 符合临床实践建议,即使用 PHQ-9A、SMFQ-儿童报告和 SMFQ-父母报告的可靠变化分数分别为 7、6 和 8。
PHQ-9A 的心理测量验证以及这些 RCI 的验证是对青少年抑郁症治疗的及时和重要贡献,通过促进 MBC 的有效使用,这是改善治疗效果的关键循证策略。