Cornelis I, Van Ham L, Gielen I, De Decker S, Bhatti S F M
Small Animal Department, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
Small Animal Department, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
Vet J. 2019 Feb;244:37-44. doi: 10.1016/j.tvjl.2018.12.007. Epub 2018 Dec 12.
Meningoencephalomyelitis of unknown origin (MUO) encompasses a group of idiopathic, most likely immune mediated, inflammatory central nervous system diseases that cause clinical, diagnostic and treatment challenges to veterinary neurologists. Clinical criteria for obtaining this presumptive diagnosis are currently available, and multiple treatment protocols have previously been investigated in small (prospective or retrospective) case series. As this group of diseases is considered fatal if left untreated, the identification of clinically usable prognostic indices could be of great value. This review provides an overview of recent developments in the clinical presentation, diagnostic findings, possible prognostic factors, treatment and outcome in dogs diagnosed with MUO.
不明原因脑膜脑脊髓炎（MUO）包括一组特发性、极有可能由免疫介导的炎症性中枢神经系统疾病，给兽医神经学家带来了临床、诊断和治疗方面的挑战。目前已有获得该初步诊断的临床标准，并且此前已在小型（前瞻性或回顾性）病例系列中研究了多种治疗方案。由于这组疾病若不治疗被认为会致命，因此识别具有临床实用性的预后指标可能具有重要价值。本综述概述了被诊断为MUO的犬在临床表现、诊断结果、可能的预后因素、治疗及转归方面的最新进展。
