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建立一个欧洲数据库,以收集有关对移民进行活动性和潜伏性结核病筛查的多国证据。

Building a European database to gather multi-country evidence on active and latent TB screening for migrants.

机构信息

Department of Public Health Science, Karolinska Institutet, 171 77 Stockholm, Sweden; Department of Communicable Disease Prevention and Control, Stockholm County Council, Smittskydd Stockholm, Box 17533, 118 91 Stockholm, Sweden.

Department of Public Health Science, Karolinska Institutet, 171 77 Stockholm, Sweden.

出版信息

Int J Infect Dis. 2019 Mar;80S:S45-S49. doi: 10.1016/j.ijid.2019.02.041. Epub 2019 Feb 28.

Abstract

BACKGROUND AND AIM

Screening for active and latent TB among migrants in low TB incidence countries may constitute an important contribution to TB elimination. E-DETECT TB, a European multi-county collaboration, aims to address the present lack of evidence on effectiveness of migrant TB screening by collating data in an international database and perform cross-country pooled and comparative analyses of screening coverage, results and linkage to care.

METHOD

A database was established using migrant TB screening data from participating countries' national screening programs, national screening pilots and local research projects. All partner countries contributed to a common agreed protocol with standardized variables, pooling available numerator and denominator screening data from participating countries and sites.

RESULTS

All collaborating members drafted and agreed upon a data sharing accord as well as a protocol that clearly defined responsibilities and data governance principles. The database has been created and data transfer is ongoing.

CONCLUSION

By persistence and focus the project has overcome considerable administrative, practical and legal challenges. This international collaboration provides greater power of analysis of harmonized data and thereby a unique opportunity to contribute migrant TB screening evidence. E-DETECT TB has started to invite other countries to contribute data to the database.

摘要

背景和目的

在结核病发病率较低的国家中,对移民进行活动性和潜伏性结核病筛查可能是结核病消除工作的一个重要贡献。E-DETECT TB 是一个欧洲多国家合作项目,旨在通过在国际数据库中整理数据并对筛查覆盖率、结果和与护理的联系进行跨国汇总和比较分析,解决目前缺乏有关移民结核病筛查效果的证据。

方法

使用参与国家的国家筛查计划、国家筛查试点和当地研究项目中的移民结核病筛查数据建立了一个数据库。所有合作伙伴国家都为一个共同商定的协议做出了贡献,该协议具有标准化的变量,汇总了来自参与国家和地点的可用分子和分母筛查数据。

结果

所有合作成员起草并同意了数据共享协议以及一份明确界定责任和数据治理原则的方案。数据库已经创建,并且数据传输正在进行中。

结论

通过坚持和专注,该项目克服了相当多的行政、实际和法律挑战。这种国际合作提供了更强大的分析能力,从而为提供移民结核病筛查证据提供了独特的机会。E-DETECT TB 已开始邀请其他国家向数据库提供数据。

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