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巴基斯坦费萨拉巴德当地人群中疟疾和伤寒的流行情况及合并感染情况。

Prevalence and co-infection of Malaria and Typhoid in the local population of Faisalabad, Pakistan.

作者信息

Jalani Hasan Abdaal, Shah Syed Muhammad Ali, Anjum Fozia, Khan Samreen Gul, Akhter Naheed, Khan Muslim, Akram Muhammad, Tahir Imtiaz Mahmood, Munir Naveed

机构信息

College of Allied Health Professional, Directorate of Medical Sciences, Government College University, Faisalabad, Pakistan.

Department of Eastern Medicine, Directorate of Medical Sciences, Government College University, Faisalabad, Pakistan.

出版信息

Pak J Pharm Sci. 2019 Jan;32(1(Supplementary)):323-326.

Abstract

Malaria and typhoid fever are among the major infectious diseases which impose significant health and socioeconomic burden on affected populations. Further, co-infection and resembling symptomatology in both infections, mostly leads to misdiagnosis and mistreatment. So co-infection of malaria and typhoid fever is becoming a major issue in tropical and subtropical countries. The current study was planned to explore the rate of co-infection of malaria and typhoid fever to show the diagnostic challenges and people health implications in the local population of Faisalabad-Pakistan. For this purpose, 144 samples (n=144) were collected from suspected subjects both male (n=74) and female (n=70) (comprises of three age group ranges viz >01-10, 11-20 and above 20 years old) of typhoid fever and malaria from October to December 2017 at Children Hospital, Faisalabad-Pakistan. Thick smear as a gold standard technique for malaria diagnosis and Widal agglutination technique for typhoid diagnosis were used. Results revealed that the prevalence of co-infection in selected subjects was 6.3% (n=9) with higher prevalence in female subjects (7.1%) as compared to males (5.4%). Further, it was also reported that age groups >01-10 years old, 11-20 years old and 21-above years old have6.6 % (n=75), 5.7 % (n=35) and 5.8% (n=34), coinfection prevalence respectively. In the present study, it could be concluded that although the prevalence of co-infection of malaria and typhoid fever in the studied population was possible but sensitivity of diagnostic tools was limited, so more reliable, specific and sensitive diagnostic tools are required to report confidently more precise correlation of these infectious diseases.

摘要

疟疾和伤寒热是对受影响人群造成重大健康和社会经济负担的主要传染病。此外,两种感染中的合并感染和相似症状大多会导致误诊和误治。因此,疟疾和伤寒热的合并感染正成为热带和亚热带国家的一个主要问题。本研究旨在探讨疟疾和伤寒热的合并感染率,以显示诊断挑战以及对巴基斯坦费萨拉巴德当地人群健康的影响。为此,2017年10月至12月期间,在巴基斯坦费萨拉巴德儿童医院,从疑似患有伤寒热和疟疾的男性(n = 74)和女性(n = 70)(包括三个年龄组范围,即1 - 10岁、11 - 20岁和20岁以上)受试者中采集了144份样本(n = 144)。采用厚涂片作为疟疾诊断的金标准技术,维达凝集技术作为伤寒诊断技术。结果显示,选定受试者中合并感染的患病率为6.3%(n = 9),女性受试者(7.1%)的患病率高于男性(5.4%)。此外,还报告称,1 - 10岁、11 - 20岁和21岁及以上年龄组的合并感染患病率分别为6.6%(n = 75)、5.7%(n = 35)和5.8%(n = 34)。在本研究中,可以得出结论,虽然在所研究人群中疟疾和伤寒热合并感染的情况可能存在,但诊断工具的敏感性有限,因此需要更可靠、特异和敏感的诊断工具,以便更准确地报告这些传染病之间更精确的相关性。

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