From the Clinical Unit of Occupational Medicine, University of Trieste, Italy.
Dermatitis. 2019 Mar/Apr;30(2):150-154. doi: 10.1097/DER.0000000000000456.
Mechanics are at higher risk to develop occupational skin diseases from exposure to irritants, oils, greases, preservatives, and metals.
The aim of the study was to investigate contact dermatitis in mechanics who underwent patch test in Northeastern Italy and compare them with white-collar workers (WCW).
From 1996 to 2016, 27,381 patients with suspected allergic contact dermatitis were patch tested in Northeastern Italy; in this group, 1270 mechanics were studied. Odds ratios (ORs) and 95% confidence interval (CI), adjusted by age and sex, were calculated assuming WCW as the reference category (n = 6933).
Mechanics represented 4.6% of the population tested. Their mean ± SD age was 36.1 ± 11.2 years. Compared with WCW, they were found to have an increased risk of occupational dermatitis (OR = 14.4; 95% CI = 11.6-18) and hand/forearm dermatitis (OR = 2.5; 95% CI = 2.3-2.9). They presented an increased risk of sensitization to epoxy resin (OR = 2.7; 95% CI = 1.5-4.8), to thiurams (OR = 2.4; 95% CI = 1.5-3.8), to 2-mercaptobenzothiazole (OR = 1.9; 95% CI = 1.1-3.4), and to diaminodiphenylmethane (OR = 1.7; 95% CI = 1.1-2.5).
Compared to WCW, mechanics were found to be at higher risk to develop occupational contact dermatitis, associated mainly to sensitization to epoxy resin and rubber accelerators.
机械师因接触刺激物、油、油脂、防腐剂和金属而患职业性皮肤病的风险更高。
本研究旨在调查意大利东北部接受斑贴试验的机械师接触性皮炎，并将其与白领工人（WCW）进行比较。
1996 年至 2016 年，意大利东北部共有 27381 名疑似过敏性接触性皮炎患者接受斑贴试验；在这组患者中，研究了 1270 名机械师。在假设 WCW 为参考类别（n=6933）的情况下，计算了调整年龄和性别后的比值比（OR）和 95%置信区间（CI）。
机械师占接受测试人群的 4.6%。他们的平均年龄±标准差为 36.1±11.2 岁。与 WCW 相比，他们患职业性皮肤病（OR=14.4；95%CI=11.6-18）和手部/前臂皮肤病（OR=2.5；95%CI=2.3-2.9）的风险增加。他们对环氧树脂（OR=2.7；95%CI=1.5-4.8）、噻二唑（OR=2.4；95%CI=1.5-3.8）、2-巯基苯并噻唑（OR=1.9；95%CI=1.1-3.4）和二氨基二苯基甲烷（OR=1.7；95%CI=1.1-2.5）的致敏风险增加。
与 WCW 相比，机械师患职业性接触性皮炎的风险更高，主要与环氧树脂和橡胶促进剂的致敏有关。
