18F-氟丁醇 PET/CT 偶然发现口咽鳞状细胞癌。

Incidentally Detected Oropharyngeal Squamous Cell Carcinoma on 18F-Fluciclovine PET/CT.

机构信息

From the Division of Nuclear Medicine, Department of Radiology and Biomedical Imaging.

Department of Pathology.

出版信息

Clin Nucl Med. 2019 May;44(5):e367-e369. doi: 10.1097/RLU.0000000000002507.

DOI:10.1097/RLU.0000000000002507

PMID:30829856

Abstract

We present a case of oropharyngeal squamous cell carcinoma (SCC) of the tongue base incidentally detected on F-fluciclovine PET/CT. A 79-year-old man with history of locally advanced prostate cancer (Gleason score 4 + 5 = 9; cT2cN1M0) previously treated with androgen deprivation therapy (luprolide + bicalutamide) presented with a slowly rising serum prostate-specific antigen over 3 years, concerning for recurrent disease. F-fluciclovine PET/CT, obtained to identify potential sites of recurrence, demonstrated prostate bed uptake with possible left seminal vesicle involvement. Additionally, an exophytic, tracer-avid right tongue base mass was incidentally noted and later confirmed to be p16+ SCC on biopsy.

摘要

我们报告了一例舌底口咽鳞状细胞癌（SCC）病例，该病例是在 F-氟代脱氧胸苷 PET/CT 上偶然发现的。一名 79 岁男性，既往患有局部晚期前列腺癌（Gleason 评分 4+5=9；cT2cN1M0），曾接受雄激素剥夺治疗（亮丙瑞林+比卡鲁胺），3 年来血清前列腺特异性抗原逐渐升高，考虑为疾病复发。进行 F-氟代脱氧胸苷 PET/CT 以确定潜在的复发部位，结果显示前列腺床摄取，可能伴有左侧精囊受累。此外，还偶然发现一个外生性、示踪剂摄取的右侧舌底肿块，随后活检证实为 p16+SCC。