18F-氟柳氯胺 PET/CT 偶然发现胃肠道间质瘤。

Gastrointestinal Stromal Tumor Incidentally Detected on 18F-Fluciclovine PET/CT.

机构信息

From the Department of Radiology and Biomedical Imaging.

Division of Abdominal Imaging, Department of Radiology, University of Washington, Seattle, WA.

出版信息

Clin Nucl Med. 2021 Apr 1;46(4):345-347. doi: 10.1097/RLU.0000000000003426.

DOI:10.1097/RLU.0000000000003426

PMID:33234933

Abstract

We present a case of metastatic gastrointestinal stromal tumor incidentally detected on 18F-fluciclovine PET/CT. A 68-year-old man with history of intermediate-risk prostate cancer (Gleason score 4 + 3 = 7; pT2cN0M0) previously treated with retropubic radical prostatectomy, adjuvant whole pelvis radiation, and androgen deprivation therapy (leuprolide) presented with slowly rising serum prostate-specific antigen over 3 years, concerning for recurrent prostate cancer. To identify potential sites of recurrent disease, an 18F-fluciclovine PET/CT was obtained. Multiple tracer-avid mesenteric masses and enlarged lymph nodes were found throughout the abdomen and pelvis, later biopsy-proven to reflect metastatic gastrointestinal stromal tumor.

摘要

我们报告了一例偶然在 18F-氟丁氨酸 PET/CT 上发现的转移性胃肠间质瘤病例。一名 68 岁男性，既往有中危前列腺癌病史（Gleason 评分 4 + 3 = 7；pT2cN0M0，行经耻骨后根治性前列腺切除术，辅助全骨盆放疗和雄激素剥夺治疗（亮丙瑞林），3 年来血清前列腺特异性抗原逐渐升高，考虑为前列腺癌复发。为了确定潜在的复发病灶，进行了 18F-氟丁氨酸 PET/CT 检查。发现腹部和骨盆多处示踪剂摄取的肠系膜肿块和增大的淋巴结，后经活检证实为转移性胃肠间质瘤。