Mastrorilli Carlo, Bernardini Roberto, Liotti Lucia, Franceschini Fabrizio, Crisafulli Giuseppe, Caimmi Silvia, Bottau Paolo, Mori Francesca, Cardinale Fabio, Saretta Francesca, Simeone Giovanni, Bergamini Marcello, Caffarelli Carlo
Clinica Pediatrica, Dipartimento di Medicina e Chirurgia, Azienda Ospedaliero-Universitaria, Università di Parma, Italy.
Acta Biomed. 2019 Jan 29;90(3-S):61-65. doi: 10.23750/abm.v90i3-S.8166.
The cause of chronic urticaria remains often elusive. The association between chronic urticaria and intake of medications have been reported in children. However, the causative role of drugs has been rarely ascertained by onset of symptoms on drug provocation test. Chronic urticaria can be mediated by immunologic and nonimmunologic mechanisms. The diagnostic work-up of chronic urticaria includes a comprehensive evaluation of triggering factors such as drugs. A diagnosis is necessary in order to permit a safely administration of drugs in children with chronic urticaria.
慢性荨麻疹的病因常常难以捉摸。儿童慢性荨麻疹与药物摄入之间的关联已有报道。然而，通过药物激发试验出现症状来确定药物的致病作用却很少见。慢性荨麻疹可由免疫和非免疫机制介导。慢性荨麻疹的诊断检查包括对药物等触发因素进行全面评估。对于患有慢性荨麻疹的儿童，为了安全用药，进行诊断是必要的。
