Sergeeva S P, Savin A A, Litvitsky P F, Lyundup A V, Kiseleva E V, Gorbacheva L R, Breslavich I D, Kucenko K I, Balyasin M V
Sechenov First Moscow State Medical University, Moscow, Russia.
Evdokimov Moscow State University of Medicine and Dentistry, Moscow, Russia.
Zh Nevrol Psikhiatr Im S S Korsakova. 2018;118(12. Vyp. 2):38-45. doi: 10.17116/jnevro201811812238.
This paper presents a literature review considering the role and mechanism of apoptosis in the pathogenesis of ischemic stroke (IS). The authors introduce a new concept: the functional request of the patient as a set of external (the nature and intensity of rehabilitation measures, characteristics of everyday life, diet, etc.) and internal (genetic factors, internal picture of the disease, availability of rental and other psychological facilities and etc.) attributes. This concept allows a new angle in understanding the pathogenesis of IS and creates fundamental and clinical potential for more successful approaches to therapy and rehabilitation after IS.
本文提出了一项关于细胞凋亡在缺血性中风（IS）发病机制中的作用和机制的文献综述。作者引入了一个新概念：将患者的功能需求视为一组外部（康复措施的性质和强度、日常生活特征、饮食等）和内部（遗传因素、疾病的内在表现、应对能力和其他心理因素等）属性。这一概念为理解IS的发病机制提供了新视角，并为IS后更成功的治疗和康复方法创造了基础和临床潜力。
