Okólska Magdalena, Róg Beata, Sałapa Kinga, Tomkiewicz-Pająk Lidia
Cardiological Outpatient Clinic, John Paul II Hospital, Cracow, Poland.
Department of Bioinformatics and Telemedicine, Jagiellonian University, Cracow, Poland.
Pol Merkur Lekarski. 2019 Feb 28;46(272):60-63.
The bicuspid aortic valve (BAV) is a congenital heart disease.
The aim of study was to evaluate the assessment of atherosclerosis risk factors in adult patients with bicuspid aortic valve compared against 30 healthy, age and sex matched volunteers.
Thirty patients (22 males, 8 females) at an average age of 27.00 ±10.6 years were compared against thirty healthy, age and sex matched volunteers. The arterial blood pressure, lipid profile, fasting glucose, inflammation markers and the lifestyle factors were analysed.
Patients with bicuspid aortic valve have a higher level of glucose (4.95 vs 4.7 mmol / l, p = 0.026) and fibrinogen (2.25 vs. 1.98 g / l, p = 0.001) compared to the control group. In the group of patients with bicuspid aortic valve there was no hypertension, diabetes, tachycardia, stress exposure, alcohol abuse and a positive family history of cardiovascular diseases.
The patients with bicuspid aortic valve have higher glucose and fibrinogen levels and they need systematic checking to reduce cardiovascular risk factors.
二叶式主动脉瓣（BAV）是一种先天性心脏病。
本研究的目的是评估成年二叶式主动脉瓣患者与30名年龄和性别匹配的健康志愿者相比的动脉粥样硬化危险因素评估情况。
将30例平均年龄为27.00±10.6岁的患者（22例男性，8例女性）与30名年龄和性别匹配的健康志愿者进行比较。分析动脉血压、血脂谱、空腹血糖、炎症标志物和生活方式因素。
与对照组相比，二叶式主动脉瓣患者的血糖水平（4.95对4.7 mmol / l，p = 0.026）和纤维蛋白原水平（2.25对1.98 g / l，p = 0.001）更高。在二叶式主动脉瓣患者组中，没有高血压、糖尿病、心动过速、压力暴露、酒精滥用和心血管疾病阳性家族史。
二叶式主动脉瓣患者的血糖和纤维蛋白原水平较高，他们需要进行系统检查以降低心血管危险因素。
