Li Yang, Kubota Yoshiki, Tashiro Mutsumi, Ohno Tatsuya
Graduate School of Medicine, Gunma University, Showa 3-39-22, Maebashi, Gunma 371-8511, Japan.
Gunma University Heavy Ion Medical Center, Gunma University, Showa 3-39-22, Maebashi, Gunma 371-8511, Japan.
Cancers (Basel). 2019 Mar 2;11(3):297. doi: 10.3390/cancers11030297.
Carbon ion radiotherapy (C-ion RT) allows excellent dose distribution because of the Bragg Peak. Compared with conventional radiotherapy, it delivers a higher dose with a smaller field. However, the dose distribution is sensitive to anatomical changes. Imaging technologies are necessary to reduce uncertainties during treatment, especially for hypofractionated and adaptive radiotherapy (ART). In-room computed tomography (CT) techniques, such as cone-beam CT (CBCT) and CT-on-rails are routinely used in photon centers and play a key role in improving treatment accuracy. For C-ion RT, there is an increasing demand for a three-dimensional (3D) image-guided system because of the limitations of the present two-dimensional (2D) imaging verification technology. This review discusses the current imaging system used in carbon ion centers and the potential benefits of a volumetric image-guided system.
碳离子放射治疗（C离子RT）由于布拉格峰而具有出色的剂量分布。与传统放射治疗相比，它能在较小的射野内给予更高的剂量。然而，剂量分布对解剖结构变化敏感。成像技术对于减少治疗期间的不确定性是必要的，特别是对于大分割放疗和自适应放疗（ART）。室内计算机断层扫描（CT）技术，如锥形束CT（CBCT）和轨道CT，在光子治疗中心被常规使用，并在提高治疗准确性方面发挥关键作用。对于C离子RT，由于目前二维（2D）成像验证技术的局限性，对三维（3D）图像引导系统的需求日益增加。本文综述了碳离子治疗中心目前使用的成像系统以及容积图像引导系统的潜在优势。
