Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Mass.
Department of Neurology and Neuroscience, University of Texas, Houston.
Am J Med. 2019 Mar;132(3):286-291. doi: 10.1016/j.amjmed.2018.10.019. Epub 2018 Oct 26.
The treatment of acute ischemic stroke includes both intravenous (IV) thrombolysis and mechanical thrombectomy. Important advances regarding both treatment modalities have occurred recently that all physicians who see patients at risk for or who have had a stroke should be aware of. This review will focus on recent clinical trials of IV thrombolysis both positive and negative. Additionally, the results of a large number of early and late time window thrombectomy trials will be presented that demonstrate the remarkable efficacy of this treatment for appropriately selected patients.
急性缺血性脑卒中的治疗包括静脉（IV）溶栓和机械取栓。最近在这两种治疗方式上都取得了重要进展，所有诊治脑卒中高危患者或已发生脑卒中的医生都应该了解这些进展。本文将重点介绍 IV 溶栓的阳性和阴性临床试验。此外，还将介绍大量早期和晚期时间窗取栓试验的结果，这些试验证明了这种治疗方法对合适选择的患者具有显著疗效。
