急性缺血性脑卒中患者血清脂蛋白水平与神经功能的关联：系统评价与荟萃分析方案
Association between serum lipoprotein levels and neurological function in patients with acute ischemic stroke: A protocol of systematic review and meta-analysis.
作者信息
Jiang Yao-Jia, Wang Zeng-Mian, Wang Ze-Yu, Wei Chun-Jie
机构信息
Third Ward of Neurology Department, First Affiliated Hospital of Jiamusi University, Jiamusi, China.
出版信息
Medicine (Baltimore). 2020 May;99(20):e20258. doi: 10.1097/MD.0000000000020258.
BACKGROUND
The target of this study is to summarize the association between the serum lipoprotein levels and neurological function in patients with acute ischemic stroke.
METHODS
A comprehensive search of Cochrane Library, PUBMED, EMBASE, Web of Science, and Chinese Biomedical Literature Database, China National Knowledge Infrastructure from inception to the February 29, 2020 without language and publication date restrictions. All searched studies will be selected by 2 authors independently against the eligibility criteria. Included studies will be critically appraised, and essential data will be extracted by 2 independent authors. If necessary, meta-analysis will be utilized to synthesize the outcome data from included articles. If it is not possible, a narrative synthesis will be undertaken.
RESULTS
This study will summarize the up-to-date evidence to investigate the association between serum lipoprotein levels and neurological function in patients with acute ischemic stroke.
CONCLUSION
Its results may present beneficial evidence and guidance for the clinical practice and further studies.
STUDY REGISTRATION NUMBER
INPLASY202040043.
背景
本研究的目的是总结急性缺血性脑卒中患者血清脂蛋白水平与神经功能之间的关联。
方法
全面检索Cochrane图书馆、PUBMED、EMBASE、Web of Science以及中国生物医学文献数据库、中国知网，检索时间从建库至2020年2月29日，无语言和出版日期限制。所有检索到的研究将由2位作者根据纳入标准独立筛选。纳入研究将进行严格评价，重要数据将由2位独立作者提取。如有必要，将采用荟萃分析来综合纳入文章的结果数据。若无法进行荟萃分析，则进行叙述性综合分析。
结果
本研究将总结最新证据，以探讨急性缺血性脑卒中患者血清脂蛋白水平与神经功能之间的关联。
结论
其结果可能为临床实践和进一步研究提供有益的证据和指导。
研究注册号
INPLASY202040043。
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