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[一名患有曼氏血吸虫病的马达加斯加患者的低补体血症性膜增生性肾小球肾炎(使用单克隆抗体检测肾小球基底膜上的血吸虫抗原)]

[Hypocomplementary membrano-proliferative glomerulonephritis in a Malagasy patient with schistosomiasis mansoni (detection of bilharzial antigen on glomerular basement membrane using monoclonal antibodies)].

作者信息

Rajaonarivelo P, Rajaona H R, Alix J L, Couderc P, Daveau C, Santoro F, Nogueira-Quetroz J A, Lovens M, Capron A, Cordonnier D

出版信息

Nephrologie. 1986;7(1):1-5.

PMID:3083279
Abstract

Schistosomiasis due to Schistosoma mansoni affects more than 40 millions people all over the world. Renal involvement is observed mainly in endemic areas. We report a case of hypocomplementemic membrano-proliferative glomerulonephritis in a malagasy man who suffered also from hepatosplenic bilharziosis. The relation between Schistosoma mansoni and the nephropathy was proved by indirect immunofluorescence test using a monoclonal antibody directed against the caecum of adult Schistosoma mansoni.

摘要

曼氏血吸虫引起的血吸虫病影响着全球超过4000万人。肾脏受累主要见于流行地区。我们报告一例患有肝脾型血吸虫病的马达加斯加男性患者出现低补体血症性膜增生性肾小球肾炎。使用针对曼氏血吸虫成虫盲肠的单克隆抗体,通过间接免疫荧光试验证实了曼氏血吸虫与肾病之间的关系。

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