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多囊卵巢综合征女性的性功能障碍:系统评价和荟萃分析。

Sexual Dysfunction in Women With Polycystic Ovary Syndrome: Systematic Review and Meta-Analysis.

机构信息

Disciplina de Ginecologia, Departamento de Obstetrícia e Ginecologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.

Disciplina de Ginecologia, Departamento de Obstetrícia e Ginecologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.

出版信息

J Sex Med. 2019 Apr;16(4):542-550. doi: 10.1016/j.jsxm.2019.01.313. Epub 2019 Mar 2.

DOI:10.1016/j.jsxm.2019.01.313
PMID:30833151
Abstract

INTRODUCTION

Sexual dysfunction occurs in any phase of sexual performance or any period of the sexual response cycle, and polycystic ovary syndrome (PCOS) affects self-image with repercussions on sexuality.

AIM

To evaluate sexual dysfunction in women with PCOS.

METHODS

A systematic review was undertaken following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis. The primary databases MEDLINE, EMBASE, Cochrane, and Lilacs were accessed using specific terms. There was no constraint against year of publication. The meta-analysis was conducted with RevMan program version 5.3.

MAIN OUTCOME MEASURE

We evaluated the relationship between sexual dysfunction and PCOS.

RESULTS

The systematic review encompassed 19 studies. The analysis indicated that 11 specific and 6 general instruments were used to measure the sexual function in PCOS women. Of these, the Female Sexual Function Index scale was used most frequently. All studies assessed different aspects of sexual performance in PCOS women, and no difference was found in between women with PCOS and control subjects.

CLINICAL IMPLICATIONS

Although there were disparities regarding ethnicity, culture, religion, and economy among studies, the available evidence failed to prove a significant link between PCOS and sexual dysfunction.

STRENGTH & LIMITATIONS: This systematic review addressed a multidimensional theme with many variables and with a wide diversity of measurement tools. Studies were small, and populations were not homogeneous.

CONCLUSION

Despite potential risk of bias, such as inhomogeneity of study population, sexual function of both PCOS patients and women with regular menstrual cycles might, in general, be similar. Firmino Murgel AC, Santos Simões R, Maciel GAR, et al. Sexual Dysfunction in Women With Polycystic Ovary Syndrome: Systematic Review and Meta-Analysis. J Sex Med 2019;16:542-550.

摘要

简介

性机能障碍发生于性表现的任何阶段或性反应周期的任何时期,多囊卵巢综合征(PCOS)会影响自我形象,从而对性行为产生影响。

目的

评估多囊卵巢综合征患者的性功能障碍。

方法

采用系统评价的首选报告项目和荟萃分析方法进行了系统评价。使用特定术语访问了主要数据库 MEDLINE、EMBASE、Cochrane 和 Lilacs,对出版年份没有限制。使用 RevMan 程序版本 5.3 进行荟萃分析。

主要观察指标

我们评估了性功能障碍与 PCOS 之间的关系。

结果

系统综述包括 19 项研究。分析表明,11 项特定工具和 6 项通用工具用于测量 PCOS 女性的性功能。其中,最常使用女性性功能指数量表。所有研究都评估了 PCOS 女性不同方面的性表现,未发现 PCOS 女性与对照组之间存在差异。

临床意义

尽管研究之间存在种族、文化、宗教和经济差异,但现有证据未能证明 PCOS 与性功能障碍之间存在显著关联。

局限性

该系统评价涉及一个多维主题,有许多变量和广泛的测量工具。研究规模较小,人群也不具有同质性。

结论

尽管存在研究人群异质性等潜在偏倚,但一般来说,PCOS 患者和月经周期正常的女性的性功能可能相似。

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