Zalzal G H, Cotton R T, McAdams A J
Otolaryngol Head Neck Surg. 1986 Feb;94(2):204-11. doi: 10.1177/019459988609400213.
Acquired subglottic stenosis in children is a difficult problem. One of the successful procedures used to correct this condition is an autogenous costal cartilage graft to the subglottis and upper trachea. The fate of the cartilage graft is not known, despite the good results of the procedure. Prompted by recovery of viable cartilage graft from two patients previously operated upon by this procedure, we performed autogenous costal cartilage grafting to the subglottic area of fifty young New Zealand rabbits, with inspection of these grafts at 2- and 4-month postoperative intervals. The purpose of this study is to prove the survival of autogenous costal cartilage grafts in the subglottic area. Gross and histologic examination 2 and 4 months postoperatively showed viable cartilage as well as lining of the graft with respiratory epithelium in the majority of cases.
儿童获得性声门下狭窄是一个难题。用于纠正这种情况的成功手术之一是将自体肋软骨移植到声门下和气管上部。尽管该手术效果良好，但软骨移植的命运尚不清楚。受两名此前接受该手术患者的存活软骨移植恢复情况的启发，我们对50只新西兰幼兔的声门下区域进行了自体肋软骨移植，并在术后2个月和4个月对这些移植进行检查。本研究的目的是证明自体肋软骨移植在声门下区域的存活情况。术后2个月和4个月的大体和组织学检查显示，在大多数病例中，软骨存活，移植部位有呼吸道上皮衬里。
