Otorhinolaryngology Department, Faculty of Medicine, Namik Kemal University, Tekirdag, Turkey.
Eur Arch Otorhinolaryngol. 2010 Aug;267(8):1247-53. doi: 10.1007/s00405-009-1189-z. Epub 2010 Jan 13.
Titanium mesh may be an alternative material to be used in laryngotracheal reconstruction. Twenty New Zealand rabbits were divided into two groups. Group A underwent laryngotracheoplasty with titanium mesh-buccal mucosa-muscle complex, and Group B received auricular cartilage grafts. All animals survived without complications. The animals were killed at 60 days, and laryngotracheal regions were evaluated. There was no subglottic collapse at physiologic and supraphysiologic negative airway pressures in Group A and mild-moderate collapse in Group B. Macroscopically the average antero-posterior and lateral diameters were not statistically different among two groups. Light microscopic examination revealed no fibrosis, necrosis or new cartilage formation in both groups. Inflammation and granulation were more pronounced in Group A. The lumens in both groups were moderately obstructed. Reconstruction of the upper airway with titanium mesh may be used in very selected cases where autologous grafting materials are inadequate and unsatisfactory.
钛网可能是喉气管重建的一种替代材料。20 只新西兰兔分为两组。A 组行钛网-颊黏膜-肌肉复合体喉气管成形术，B 组行耳软骨移植。所有动物均无并发症存活。动物在 60 天时被杀，对喉气管区域进行评估。在生理和超生理负气道压力下，A 组无会厌下塌，B 组有轻度至中度塌。大体上，两组的前后径和横径无统计学差异。光镜检查两组均未见纤维化、坏死或新软骨形成。A 组炎症和肉芽组织更明显。两组的管腔均中度阻塞。在自体移植物材料不足和不满意的非常选择情况下，可使用钛网重建上呼吸道。
