Sebastião Emerson, Pilutti Lara A, Motl Robert W
Int J MS Care. 2019 Jan-Feb;21(1):23-28. doi: 10.7224/1537-2073.2017-078.
There is ample evidence that aerobic fitness is reduced in people with multiple sclerosis (MS), and this may yield a reduction in independence in instrumental activities of daily living (IADLs). This study examined the association between aerobic fitness and self-reported IADLs in persons with MS.
Sixty-two adults with MS completed an incremental exercise test as a measure of aerobic fitness (peak oxygen consumption), a demographic questionnaire, and an IADL scale and underwent a neurologic examination for characterization of disability level (ie, Expanded Disability Status Scale) in a single session.
The analysis revealed a weak but significant association between aerobic fitness and total IADL score ( = 0.28 [95% CI, 0.03-0.49], = .033). Those reporting dependence in different IADL categories (eg, shopping, food preparation, housekeeping, laundry, and responsibility for own medication) presented with lower aerobic fitness compared with those reporting independence, although the difference was not statistically significant.
These findings extend previous studies on activities of daily living in people with MS and underscore the need for studies examining the potential effect of aerobic exercise interventions on independence regarding IADLs in this population.
有充分证据表明，多发性硬化症（MS）患者的有氧适能会降低，这可能导致其在工具性日常生活活动（IADL）中的独立性下降。本研究调查了MS患者的有氧适能与自我报告的IADL之间的关联。
62名成年MS患者在一次检查中完成了一项递增运动测试，以测量有氧适能（峰值耗氧量），填写了一份人口统计学调查问卷和一份IADL量表，并接受了神经系统检查以确定残疾水平（即扩展残疾状态量表）。
分析显示，有氧适能与IADL总分之间存在微弱但显著的关联（r = 0.28 [95% CI，0.03 - 0.49]，P = 0.033）。与报告独立的患者相比，报告在不同IADL类别（如购物、食物准备、家务、洗衣和自行用药责任）中存在依赖的患者有氧适能较低，尽管差异无统计学意义。
这些发现扩展了先前关于MS患者日常生活活动的研究，并强调有必要开展研究，以检验有氧运动干预对该人群IADL独立性的潜在影响。
