Reply to 'Comment on 'Cardiac effects of 6 months' dietary nitrate and spironolactone in patients with hypertension and with/at risk of type 2 diabetes, in the factorial design, double-blind, randomised controlled VaSera trial' by Faconti et al.'.
作者信息
Faconti Luca, Cruickshank J Kennedy, Webb Andrew James
机构信息
King's College London British Heart Foundation Centre, Department of Clinical Pharmacology, School of Cardiovascular Medicine and Sciences, London, UK.
Department of Nutritional Sciences, School of Life Course Sciences, King's College London, London, UK.
出版信息
Br J Clin Pharmacol. 2019 May;85(5):1037-1038. doi: 10.1111/bcp.13890. Epub 2019 Mar 4.
Abstract
摘要
相似文献
1
Reply to 'Comment on 'Cardiac effects of 6 months' dietary nitrate and spironolactone in patients with hypertension and with/at risk of type 2 diabetes, in the factorial design, double-blind, randomised controlled VaSera trial' by Faconti et al.'.对法孔蒂等人《对“在析因设计、双盲、随机对照的VaSera试验中，6个月膳食硝酸盐和螺内酯对高血压合并2型糖尿病及有2型糖尿病风险患者的心脏影响”的评论》的回复
Br J Clin Pharmacol. 2019 May;85(5):1037-1038. doi: 10.1111/bcp.13890. Epub 2019 Mar 4.
2
Comment on 'Cardiac effects of 6 months' dietary nitrate and spironolactone in patients with hypertension and with/at risk of type 2 diabetes, in the factorial design, double-blind, randomised controlled VaSera trial' by Faconti et al.对法孔蒂等人的《在析因设计、双盲、随机对照的VaSera试验中，6个月膳食硝酸盐和螺内酯对高血压合并2型糖尿病及有2型糖尿病风险患者的心脏影响》的评论
Br J Clin Pharmacol. 2019 May;85(5):1035-1036. doi: 10.1111/bcp.13835. Epub 2019 Jan 4.
3
Cardiac effects of 6 months' dietary nitrate and spironolactone in patients with hypertension and with/at risk of type 2 diabetes, in the factorial design, double-blind, randomized controlled VaSera trial.在因子设计、双盲、随机对照 VaSera 试验中，研究了 6 个月饮食硝酸盐和螺内酯对高血压伴/有 2 型糖尿病风险患者的心脏影响。
Br J Clin Pharmacol. 2019 Jan;85(1):169-180. doi: 10.1111/bcp.13783. Epub 2018 Nov 13.
4
Low dose spironolactone reduces blood pressure in patients with resistant hypertension and type 2 diabetes mellitus: a double blind randomized clinical trial.低剂量螺内酯可降低耐药性高血压合并 2 型糖尿病患者的血压：一项双盲随机临床试验。
J Hypertens. 2013 Oct;31(10):2094-102. doi: 10.1097/HJH.0b013e3283638b1a.
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Reducing Arterial Stiffness Independently of Blood Pressure: The VaSera Trial.独立于血压降低动脉僵硬度：VaSera试验
J Am Coll Cardiol. 2017 Sep 26;70(13):1683-1684. doi: 10.1016/j.jacc.2017.07.765.
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Low-dose spironolactone reduces plasma fibulin-1 levels in patients with type 2 diabetes and resistant hypertension.低剂量螺内酯可降低2型糖尿病合并顽固性高血压患者的血浆纤连蛋白-1水平。
J Hum Hypertens. 2015 Jan;29(1):28-32. doi: 10.1038/jhh.2014.27. Epub 2014 Apr 17.
7
Letter regarding article by Hood et al, "The Spironolactone, Amiloride, Losartan, and Thiazide (SALT) double-blind crossover trial in patients with low-renin hypertension and elevated aldosterone-renin ratio".关于胡德等人所著文章《螺内酯、阿米洛利、氯沙坦与噻嗪类药物（SALT）治疗低肾素性高血压及醛固酮-肾素比值升高患者的双盲交叉试验》的信函
Circulation. 2008 Feb 5;117(5):e151; author reply e152. doi: 10.1161/CIRCULATIONAHA.107.738757.
8
Sodium restriction and blood pressure in hypertensive type II diabetics: randomised blind controlled and crossover studies of moderate sodium restriction and sodium supplementation.II型糖尿病高血压患者的钠限制与血压：适度钠限制和钠补充的随机双盲对照及交叉研究
BMJ. 1989 Jan 28;298(6668):227-30. doi: 10.1136/bmj.298.6668.227.
9
A double-blind, randomized study comparing the antihypertensive effect of eplerenone and spironolactone in patients with hypertension and evidence of primary aldosteronism.一项比较依普利酮和螺内酯在高血压合并原发性醛固酮增多症患者降压效果的双盲、随机研究。
J Hypertens. 2011 May;29(5):980-90. doi: 10.1097/HJH.0b013e3283455ca5.
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Addition of spironolactone in patients with resistant arterial hypertension (ASPIRANT): a randomized, double-blind, placebo-controlled trial.螺内酯治疗抵抗性动脉高血压患者（ASPIRANT）：一项随机、双盲、安慰剂对照试验。
Hypertension. 2011 Jun;57(6):1069-75. doi: 10.1161/HYPERTENSIONAHA.111.169961. Epub 2011 May 2.
本文引用的文献
1
Comment on 'Cardiac effects of 6 months' dietary nitrate and spironolactone in patients with hypertension and with/at risk of type 2 diabetes, in the factorial design, double-blind, randomised controlled VaSera trial' by Faconti et al.对法孔蒂等人的《在析因设计、双盲、随机对照的VaSera试验中，6个月膳食硝酸盐和螺内酯对高血压合并2型糖尿病及有2型糖尿病风险患者的心脏影响》的评论
Br J Clin Pharmacol. 2019 May;85(5):1035-1036. doi: 10.1111/bcp.13835. Epub 2019 Jan 4.
2
Cardiac effects of 6 months' dietary nitrate and spironolactone in patients with hypertension and with/at risk of type 2 diabetes, in the factorial design, double-blind, randomized controlled VaSera trial.在因子设计、双盲、随机对照 VaSera 试验中，研究了 6 个月饮食硝酸盐和螺内酯对高血压伴/有 2 型糖尿病风险患者的心脏影响。
Br J Clin Pharmacol. 2019 Jan;85(1):169-180. doi: 10.1111/bcp.13783. Epub 2018 Nov 13.
3
Nitrite exerts antioxidant effects, inhibits the mTOR pathway and reverses hypertension-induced cardiac hypertrophy.亚硝酸盐发挥抗氧化作用，抑制 mTOR 通路，逆转高血压引起的心肌肥厚。
Free Radic Biol Med. 2018 May 20;120:25-32. doi: 10.1016/j.freeradbiomed.2018.03.006. Epub 2018 Mar 9.
4
Inorganic Nitrite Selectively Dilates Epicardial Coronary Arteries.无机亚硝酸盐可选择性扩张心外膜冠状动脉。
J Am Coll Cardiol. 2018 Jan 23;71(3):363-364. doi: 10.1016/j.jacc.2017.10.093.
5
Reducing Arterial Stiffness Independently of Blood Pressure: The VaSera Trial.独立于血压降低动脉僵硬度：VaSera试验
J Am Coll Cardiol. 2017 Sep 26;70(13):1683-1684. doi: 10.1016/j.jacc.2017.07.765.
6
Mechanistic target of rapamycin modulation: an emerging therapeutic approach in a wide variety of disease processes.雷帕霉素作用机制的调控：一种在多种疾病进程中新兴的治疗方法。
Br J Clin Pharmacol. 2016 Nov;82(5):1156-1157. doi: 10.1111/bcp.13117.
7
It is rocket science - why dietary nitrate is hard to 'beet'! Part II: further mechanisms and therapeutic potential of the nitrate-nitrite-NO pathway.这可是高深莫测的学问——为何膳食硝酸盐难以被超越！第二部分：硝酸盐-亚硝酸盐-一氧化氮途径的进一步机制及治疗潜力
Br J Clin Pharmacol. 2017 Jan;83(1):140-151. doi: 10.1111/bcp.12918. Epub 2016 May 6.
8
It is rocket science - why dietary nitrate is hard to 'beet'! Part I: twists and turns in the realization of the nitrate-nitrite-NO pathway.这可是个高深莫测的问题——为什么膳食硝酸盐难以被“超越”！第一部分：硝酸盐-亚硝酸盐-一氧化氮途径认识过程中的波折。
Br J Clin Pharmacol. 2017 Jan;83(1):129-139. doi: 10.1111/bcp.12913. Epub 2016 May 6.
9
Paradoxical normoxia-dependent selective actions of inorganic nitrite in human muscular conduit arteries and related selective actions on central blood pressures.无机亚硝酸盐在人体肌性输送血管中依赖反常性氧合的选择性作用及其对中心血压的相关选择性作用。
Circulation. 2015 Jan 27;131(4):381-9; discussion 389. doi: 10.1161/CIRCULATIONAHA.114.009554. Epub 2014 Dec 22.
10
Myocardial wall stress: from hypertension to heart tension.
Hypertension. 2012 Jul;60(1):10-1. doi: 10.1161/HYPERTENSIONAHA.112.193839. Epub 2012 Jun 4.
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