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Maturational changes in vancomycin protein binding affect vancomycin dosing in neonates.

作者信息

Leroux Stéphanie, van den Anker Johannes N, Smits Anne, Pfister Marc, Allegaert Karel

机构信息

Pediatric Pharmacology and Pharmacometrics, University Children's Hospital Basel, University of Basel, Basel, Switzerland.

Neonatal Intensive Care Unit, University Hospital Rennes, Rennes, France.

出版信息

Br J Clin Pharmacol. 2019 May;85(5):865-867. doi: 10.1111/bcp.13899. Epub 2019 Mar 4.

Abstract
摘要

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Factors impacting unbound vancomycin concentrations in neonates and young infants.
Eur J Clin Microbiol Infect Dis. 2018 Aug;37(8):1503-1510. doi: 10.1007/s10096-018-3277-8. Epub 2018 May 16.
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Unanswered Questions Regarding Optimal Pediatric Vancomycin Use.
Ther Drug Monit. 2016 Jun;38(3):419-20. doi: 10.1097/FTD.0000000000000289.
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Use of antibacterial agents in the neonate: 50 years of experience with vancomycin administration.
Semin Fetal Neonatal Med. 2013 Feb;18(1):28-34. doi: 10.1016/j.siny.2012.10.003. Epub 2012 Nov 6.
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Renal drug clearance in preterm neonates: relation to prenatal growth.
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