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Reports of gabapentin and pregabalin abuse, misuse, dependence, or overdose: An analysis of the Food And Drug Administration Adverse Events Reporting System (FAERS).报告加巴喷丁和普瑞巴林滥用、误用、依赖或过量：对食品和药物管理局不良事件报告系统（FAERS）的分析。
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Dose ranging effects of pregabalin on pain in patients undergoing laparoscopic hysterectomy: A randomized, double blinded, placebo controlled, clinical trial.普瑞巴林对腹腔镜子宫切除术患者疼痛的剂量范围效应：一项随机、双盲、安慰剂对照的临床试验。
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Br J Clin Pharmacol. 2019 Jun;85(6):1260-1269. doi: 10.1111/bcp.13892. Epub 2019 Mar 28.

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A case report of pregabalin misuse leading to drug dependence.一例普瑞巴林滥用致药物依赖的病例报告。
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Pharmacotherapy of Anxiety Disorders: Current and Emerging Treatment Options.焦虑症的药物治疗：当前及新出现的治疗选择
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Exploring the Baseline Knowledge and Experience of Healthcare Professionals in the United Kingdom on Novel Psychoactive Substances.探索英国医疗保健专业人员对新型精神活性物质的基线知识和经验。
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本文引用的文献

1
Pregabalin misuse-related ambulance attendances in Victoria, 2012-2017: characteristics of patients and attendances.2012-2017 年维多利亚州与普瑞巴林滥用相关的救护车就诊情况：患者和就诊特征。
Med J Aust. 2019 Feb;210(2):75-79. doi: 10.5694/mja2.12036. Epub 2018 Nov 22.
2
Rising pregabalin use and misuse in Australia: trends in utilization and intentional poisonings.澳大利亚普瑞巴林使用和滥用情况不断增加：利用和故意中毒趋势。
Addiction. 2019 Jun;114(6):1026-1034. doi: 10.1111/add.14412. Epub 2018 Sep 5.
3
Abuse of Prescription Drugs in the Context of Novel Psychoactive Substances (NPS): A Systematic Review.新型精神活性物质（NPS）背景下的处方药滥用：一项系统综述
Brain Sci. 2018 Apr 22;8(4):73. doi: 10.3390/brainsci8040073.
4
How addictive are gabapentin and pregabalin? A systematic review.加巴喷丁和普瑞巴林的成瘾性如何？系统评价。
Eur Neuropsychopharmacol. 2017 Dec;27(12):1185-1215. doi: 10.1016/j.euroneuro.2017.08.430. Epub 2017 Oct 5.
5
Pregabalin Use Among Users of Illicit Drugs: A Cross-Sectional Survey in Southern Germany. pregabalin 在非法药物使用者中的使用情况：德国南部的一项横断面调查。
CNS Drugs. 2017 Oct;31(10):891-898. doi: 10.1007/s40263-017-0467-3.
6
Addiction-related interactions of pregabalin with morphine in mice and humans: reinforcing and inhibiting effects.普瑞巴林与吗啡在小鼠和人体中的成瘾相关相互作用：增强和抑制效应。
Addict Biol. 2018 May;23(3):945-958. doi: 10.1111/adb.12538. Epub 2017 Jul 25.
7
Benzodiazepine, z-drug and pregabalin prescriptions and mortality among patients in opioid maintenance treatment-A nation-wide register-based open cohort study.苯二氮䓬类药物、Z 类药物和普瑞巴林处方与接受阿片类药物维持治疗患者的死亡率——一项基于全国登记的开放性队列研究
Drug Alcohol Depend. 2017 May 1;174:58-64. doi: 10.1016/j.drugalcdep.2017.01.013. Epub 2017 Feb 28.
8
Misuse of the γ-aminobutyric acid analogues baclofen, gabapentin and pregabalin in the UK.γ-氨基丁酸类似物巴氯芬、加巴喷丁和普瑞巴林在英国的滥用情况。
Br J Clin Pharmacol. 2014 Jul;78(1):190-1. doi: 10.1111/bcp.12277.
9
Profiles of pregabalin and gabapentin abuse by postmortem toxicology.尸检毒理学中普瑞巴林和加巴喷丁的滥用情况剖析
Forensic Sci Int. 2014 Aug;241:1-6. doi: 10.1016/j.forsciint.2014.04.028. Epub 2014 May 5.
10
Pregabalin abuse among opiate addicted patients.阿片类药物成瘾患者中普瑞巴林的滥用。
Eur J Clin Pharmacol. 2013 Dec;69(12):2021-5. doi: 10.1007/s00228-013-1578-5. Epub 2013 Aug 30.

Pregabalin: A range of misuse-related unanswered questions.

作者信息

Schifano Fabrizio, Chiappini Stefania

机构信息

Psychopharmacology, Drug Misuse and Novel Psychoactive Substances Research Unit, School of Life and Medical Sciences, University of Hertfordshire, Hatfield, UK.

出版信息

CNS Neurosci Ther. 2019 May;25(5):659-660. doi: 10.1111/cns.13115. Epub 2019 Mar 4.

DOI:10.1111/cns.13115
PMID:30834646
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6488882/
Abstract
摘要