Limandri Barbara J
J Psychosoc Nurs Ment Health Serv. 2019 Mar 1;57(3):7-10. doi: 10.3928/02793695-20190218-02.
Long-acting injectable (LAI) antipsychotic medications have been around since the 1960s as alternatives to oral formulations to improve medication adherence. LAIs are similar enough to their corresponding oral formulations to be used interchangeably and have convincing evidence of improving consistency in pharmacotherapy that reduces the rates of relapse and frequency of hospitalization for individuals with psychosis. So why are they not used as often? The current article presents an argument to initiate LAIs early in treatment as a way of establishing consistency in treatment, thereby, potentially improving client outcomes. [Journal of Psychosocial Nursing and Mental Health Services, 57(3), 7-10.].
长效注射用（LAI）抗精神病药物自20世纪60年代以来就已存在，作为口服制剂的替代品以提高药物依从性。长效注射剂与其相应的口服制剂非常相似，可以互换使用，并且有令人信服的证据表明，它能提高药物治疗的一致性，从而降低精神病患者的复发率和住院频率。那么，为什么它们没有得到广泛应用呢？本文提出了一个观点，即在治疗早期就开始使用长效注射剂，以此建立治疗的一致性，从而有可能改善患者的治疗效果。[《心理社会护理与精神卫生服务杂志》，第57卷第3期，第7 - 10页]
