Division of Vascular Surgery, University of Ottawa, Ottawa, Ontario, Canada.
Division of Vascular Surgery, University of Ottawa, Ottawa, Ontario, Canada.
J Vasc Surg. 2019 Sep;70(3):756-761.e1. doi: 10.1016/j.jvs.2018.11.036. Epub 2019 Mar 2.
Infrarenal aortic neck angulation is one of the most powerful predictors of endovascular aneurysm repair failure. Whereas the "gold standard" to measure this angle is three-dimensional (3D) reconstruction and centerline measurement, many surgeons rely on estimations of angulation based on two-dimensional (2D) views of computed tomography imaging. Unfortunately, these views do not accurately represent the true angle, particularly if aortic angulation is oblique to the standard views. In response to this issue, our group has developed a novel trigonometric formula that uses coronal and sagittal measured angles to calculate the true angle. The purpose of this study was to compare the paired angle formula with 3D centerline measurements for estimating true aortic neck angulation.
Fifty randomly selected patients treated by endovascular aneurysm repair at The Ottawa Hospital between 2010 and 2015 were studied. The 3D centerline aortic neck angle measurements were made by a radiology staff physician. The paired angle formula was applied by a vascular surgeon, resident, and student using 2D coronal and sagittal angles from computed tomography imaging to estimate the true angle.
The average age was 78 years; 74% of patients were male, and average preoperative aneurysm diameter was 5.7 cm. The mean neck length was 1.9 cm (1.1-3.2 cm), and mean neck angulation calculated by the gold standard measurements was 39 degrees (2-84 degrees). Linear regression demonstrated strong association between 3D measurements and the paired angle formula, with correlations comparable to the intraobserver variability (intraclass correlation coefficient values range, 0.74-0.87). The average user estimates deviated minimally from the gold standard (absolute difference, 6 degrees; 95% confidence interval, 4-8 degrees) without systemic bias. The paired angle formula accurately ruled out severe angulation >60 degrees with an overall negative predictive value of >99%. Compared with isolated 2D measurements, application of the paired angle formula significantly decreased the false-negative rate of unappreciated severe angulation >60 degrees from 4.8% to 0.7% (P = .032).
The paired angle formula detects significantly more severe angles than isolated 2D measurements and can accurately rule out severe angulation >60 degrees compared with the 3D measurements. The implementation of this angle estimation method is a useful adjunct in the measurement of aortic neck angulation, especially if 3D reconstruction software is not readily available. Furthermore, the importance of accurate angle measurement is not limited to vascular surgery and has direct relevance to any procedural specialty that relies on preoperative angle measurements.
腹主动脉瘤颈角是血管内修复失败的最强预测因素之一。虽然测量这个角度的“金标准”是三维(3D)重建和中心线测量,但许多外科医生依赖于基于 CT 成像二维(2D)视图的角度估计。不幸的是,这些视图不能准确地表示真实角度,特别是如果主动脉角度与标准视图成斜角。针对这个问题,我们的团队开发了一种新的三角公式,该公式使用冠状面和矢状面测量角度来计算真实角度。本研究的目的是比较配对角公式与 3D 中心线测量值,以估计真实的主动脉瘤颈角。
选择 2010 年至 2015 年间在渥太华医院接受血管内动脉瘤修复治疗的 50 例随机患者进行研究。由放射科医生进行 3D 中心线主动脉瘤颈角度测量。使用来自 CT 成像的 2D 冠状面和矢状面角度,由血管外科医生、住院医生和学生应用配对角公式来估计真实角度。
平均年龄为 78 岁;74%的患者为男性,平均术前动脉瘤直径为 5.7cm。颈长平均为 1.9cm(1.1-3.2cm),金标准测量的颈角平均为 39 度(2-84 度)。线性回归显示 3D 测量值与配对角公式之间存在很强的相关性,相关性与观察者内变异性相当(组内相关系数值范围为 0.74-0.87)。用户估计值与金标准值的平均差异很小(绝对差值为 6 度;95%置信区间为 4-8 度),没有系统偏差。配对角公式可以准确排除>60 度的严重角度,总体阴性预测值>99%。与单独的 2D 测量相比,应用配对角公式可将未被识别的>60 度严重角度的假阴性率从 4.8%显著降低至 0.7%(P=.032)。
配对角公式比单独的 2D 测量检测到更多的严重角度,并且与 3D 测量相比,能够准确排除>60 度的严重角度。与 3D 重建软件相比,这种角度估计方法的应用是主动脉瘤颈角测量的有用补充,特别是在 3D 重建软件不可用时。此外,准确测量角度的重要性不仅限于血管外科,与任何依赖术前角度测量的手术专业都有直接关系。